Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 638676..639207 Replicon chromosome
Accession NZ_CP062231
Organism Rhizobium sp. TH2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IHQ71_RS03275 Protein ID WP_258160459.1
Coordinates 638926..639207 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag IHQ71_RS03270 Protein ID WP_258160458.1
Coordinates 638676..638939 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHQ71_RS03255 (IHQ71_03250) 634487..635899 + 1413 WP_258160455.1 hypothetical protein -
IHQ71_RS03260 (IHQ71_03255) 635983..637419 + 1437 WP_258160456.1 FAD-linked oxidase C-terminal domain-containing protein -
IHQ71_RS03265 (IHQ71_03260) 637419..638621 + 1203 WP_258160457.1 glycolate oxidase subunit GlcE -
IHQ71_RS03270 (IHQ71_03265) 638676..638939 + 264 WP_258160458.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
IHQ71_RS03275 (IHQ71_03270) 638926..639207 + 282 WP_258160459.1 type II toxin-antitoxin system YafQ family toxin Toxin
IHQ71_RS03280 (IHQ71_03275) 639214..640512 + 1299 WP_258160460.1 glycolate oxidase subunit GlcF -
IHQ71_RS03285 (IHQ71_03280) 640566..641033 + 468 WP_258160462.1 hypothetical protein -
IHQ71_RS03290 (IHQ71_03285) 641058..641720 - 663 WP_258160463.1 outer membrane beta-barrel protein -
IHQ71_RS03295 (IHQ71_03290) 641924..642577 - 654 WP_258162726.1 L,D-transpeptidase -
IHQ71_RS03300 (IHQ71_03295) 642779..643513 - 735 WP_258160465.1 L,D-transpeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10858.55 Da        Isoelectric Point: 9.1585

>T173620 WP_258160459.1 NZ_CP062231:638926-639207 [Rhizobium sp. TH2]
MRTIKFSNKFKRDYKREKSGRSAKNLDPLLNEIVQILVADEQLPRKNFDHPLTGNWIDCRDCHVRPDLVLIYRKLGDDVL
ELVRLGSHSELGL

Download         Length: 282 bp

>T173620 NZ_CP080253:981754-982089 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9494.81 Da        Isoelectric Point: 4.2463

>AT173620 WP_258160458.1 NZ_CP062231:638676-638939 [Rhizobium sp. TH2]
MSENAVVRARINEDVKNEASAVLDAMGLTVSDAFRMMMVRIAREKALPFDPLIPNDETIEAIKAARRGELTTVGSVDELF
ASLNADD

Download         Length: 264 bp

>AT173620 NZ_CP080253:981506-981754 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References