Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 5979342..5980212 Replicon chromosome
Accession NZ_CP062229
Organism Mesorhizobium onobrychidis strain OM4

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag IHQ72_RS29530 Protein ID WP_258119032.1
Coordinates 5979342..5979848 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag IHQ72_RS29535 Protein ID WP_095492412.1
Coordinates 5979841..5980212 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHQ72_RS29505 (IHQ72_29235) 5975176..5976078 - 903 WP_258119027.1 cytochrome c oxidase subunit II -
IHQ72_RS29510 (IHQ72_29240) 5976454..5977029 + 576 WP_258119029.1 invasion associated locus B family protein -
IHQ72_RS29515 (IHQ72_29245) 5977040..5977531 + 492 WP_258119030.1 GNAT family N-acetyltransferase -
IHQ72_RS29520 (IHQ72_29250) 5977615..5979027 + 1413 WP_258119031.1 metalloprotease TldD -
IHQ72_RS29525 (IHQ72_29255) 5979073..5979353 + 281 Protein_5835 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
IHQ72_RS29530 (IHQ72_29260) 5979342..5979848 - 507 WP_258119032.1 RES domain-containing protein Toxin
IHQ72_RS29535 (IHQ72_29265) 5979841..5980212 - 372 WP_095492412.1 DUF2384 domain-containing protein Antitoxin
IHQ72_RS29540 (IHQ72_29270) 5980298..5981539 - 1242 WP_258119034.1 class I SAM-dependent RNA methyltransferase -
IHQ72_RS29545 (IHQ72_29275) 5981536..5982330 - 795 WP_192360687.1 TlyA family RNA methyltransferase -
IHQ72_RS29550 (IHQ72_29280) 5982505..5982906 + 402 WP_258119036.1 GFA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(8-161)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18876.51 Da        Isoelectric Point: 7.4357

>T173618 WP_258119032.1 NZ_CP062229:c5979848-5979342 [Mesorhizobium onobrychidis]
MPESRLSLWRAFVPRWAHLPLSGEGAARFGGRWNPVGTPAIYAARELSTAWAEYNQGFVQHPALIAQLELSGARLADLTD
ADVLTKFGVTADIHRCEWRDIMDQGLVPDTHTLRDRLIADRQHGVIYPSFMSPGGTCVALWRWNESNAPRLKIIDPDHRL
PKTPASWL

Download         Length: 507 bp

>T173618 NZ_CP080253:639543-639857 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13238.33 Da        Isoelectric Point: 10.2173

>AT173618 WP_095492412.1 NZ_CP062229:c5980212-5979841 [Mesorhizobium onobrychidis]
MNTAALDIRASRFGEERTPFLSARRVAELLGVNLTELAGLIGVARNTLAAKTGARKVDAALSPIVRILAMAGEMAGDEQR
AAIWFKHQPIPGWAGKTAYDLVREGKTDKVLAYLEAVRSGIYA

Download         Length: 372 bp

>AT173618 NZ_CP080253:639854-640270 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References