Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2068080..2068533 Replicon chromosome
Accession NZ_CP062222
Organism Brevundimonas goettingensis strain LVF2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IFJ75_RS10275 Protein ID WP_207867893.1
Coordinates 2068261..2068533 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IFJ75_RS10270 Protein ID WP_207867891.1
Coordinates 2068080..2068268 (+) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IFJ75_RS10255 (IFJ75_10240) 2064442..2066715 - 2274 WP_207867884.1 S9 family peptidase -
IFJ75_RS10260 (IFJ75_10245) 2066836..2067660 + 825 WP_207867886.1 ferredoxin--NADP reductase -
IFJ75_RS10265 (IFJ75_10250) 2067723..2068055 + 333 WP_207867889.1 chorismate mutase -
IFJ75_RS10270 (IFJ75_10255) 2068080..2068268 + 189 WP_207867891.1 antitoxin Antitoxin
IFJ75_RS10275 (IFJ75_10260) 2068261..2068533 + 273 WP_207867893.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IFJ75_RS10280 (IFJ75_10265) 2068530..2068883 - 354 WP_207867898.1 Hpt domain-containing protein -
IFJ75_RS10285 (IFJ75_10270) 2068883..2070322 - 1440 WP_207867900.1 amino acid permease -
IFJ75_RS10295 (IFJ75_10280) 2070834..2071289 + 456 WP_225896770.1 helix-turn-helix transcriptional regulator -
IFJ75_RS10300 (IFJ75_10285) 2071347..2071502 + 156 WP_207867902.1 hypothetical protein -
IFJ75_RS10305 2071714..2071971 - 258 WP_207867904.1 hypothetical protein -
IFJ75_RS10310 (IFJ75_10290) 2072074..2072379 - 306 WP_225896771.1 UBP-type zinc finger domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10269.90 Da        Isoelectric Point: 11.7439

>T173585 WP_207867893.1 NZ_CP062222:2068261-2068533 [Brevundimonas goettingensis]
MTRVVWSRRALQNINAIRAYVGQFSPLAAQRLALRLRNAGETLRDFPERGMAMSGARRQLTTVPPYLIRYIYRDSVVSIL
EVRHAAEDAP

Download         Length: 273 bp

>T173585 NZ_CP080247:3558385-3558726 [Escherichia sp. TM-G17TGC]
ATGAAAACTTTACCTGCAATAACTCAGCGGGCGGTGAAGCCCTGCCTGTCACCCGTGGCTGTCTGGCAAATGTTACTGAC
ACGTCTGCTGGAACAGCACTATGGTCTGACAATAAACGACACGCCATTCTGCAATGAGGCTGTGATTAAGGAACACATCG
ATGCCGGTATCACCCTAGCCGATGCCGTGAATTTTCTGGTAGAAAAATACGAGCTGGTTCGTATCGACAGGAAGGGATTT
AGCTGGCAGGAACAATCTCCTTATCTCCGGGCTGCAGACATTCTGCGAGCGCGGCAGGCAACTGGCTTGTTGCGGCAAAG
CCGTAACAACGTAGTACGATGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 6696.33 Da        Isoelectric Point: 3.7802

>AT173585 WP_207867891.1 NZ_CP062222:2068080-2068268 [Brevundimonas goettingensis]
MAKPEPSIFETPDPDAEERSLLEGEADVAAGRVIPHEEVAKWLATWGTPEEGPPPASWGLDD

Download         Length: 189 bp

>AT173585 NZ_CP080247:3558047-3558364 [Escherichia sp. TM-G17TGC]
ATGAGCAACCCTACCAGGGGCCTGCAGCGGGAGATTACACTGCGCCTGGGAGCCCGTCTGGTGCAGGAAGGCAACCGACT
GCATTATCTGGCTGACCGGGCCAGCATCACCGGCAAGTTCAGTGACATCGAATGCCGGAAGCTGGATGAAACATTCCCGC
ACTTTATCCTCCAGATGGAATCGATGCTGACCACCGGTGAACTCAGCCCCCACCATGCCCACTGCGTTACCCTGTACCAC
AACGATTTAACCTGCGAAGCCGACACCCTTGGCAGTTGCGGCTACGTATACATCGCCATTTACCCCACTCAGCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References