Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1036383..1036930 Replicon chromosome
Accession NZ_CP062221
Organism Cellulomonas palmilytica strain EW123

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag F1D97_RS04960 Protein ID WP_236122620.1
Coordinates 1036655..1036930 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag F1D97_RS04955 Protein ID WP_236122619.1
Coordinates 1036383..1036658 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1D97_RS04940 (F1D97_04885) 1032607..1033254 - 648 WP_236122611.1 GNAT family N-acetyltransferase -
F1D97_RS04945 (F1D97_04890) 1033251..1034663 - 1413 WP_236122613.1 SidA/IucD/PvdA family monooxygenase -
F1D97_RS04950 (F1D97_04895) 1034660..1036108 - 1449 WP_236122617.1 pyridoxal-dependent decarboxylase -
F1D97_RS04955 (F1D97_04900) 1036383..1036658 + 276 WP_236122619.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
F1D97_RS04960 (F1D97_04905) 1036655..1036930 + 276 WP_236122620.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F1D97_RS04965 (F1D97_04910) 1036996..1037847 - 852 WP_236122622.1 LysR family substrate-binding domain-containing protein -
F1D97_RS04970 (F1D97_04915) 1037844..1038590 - 747 WP_236122629.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
F1D97_RS17410 (F1D97_04920) 1038647..1040143 + 1497 WP_263008798.1 chloride channel protein -
F1D97_RS04980 (F1D97_04925) 1040173..1041135 + 963 WP_236123490.1 cation diffusion facilitator family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(10-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10352.86 Da        Isoelectric Point: 10.2266

>T173584 WP_236122620.1 NZ_CP062221:1036655-1036930 [Cellulomonas palmilytica]
VSEAAEPWRVQVAPSAIRSLDRLPPRVAGAVVEFVTRTLPANPERMSKPLRYELEGLRSARRGDYRVLFTLDDDTHVLLV
VRISHRADAYR

Download         Length: 276 bp

>T173584 NZ_CP080247:3439709-3439927 [Escherichia sp. TM-G17TGC]
ATGTCCGAAAAATTTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9914.12 Da        Isoelectric Point: 4.8259

>AT173584 WP_236122619.1 NZ_CP062221:1036383-1036658 [Cellulomonas palmilytica]
MRTVALSEAKDRLSALVDEADRTHEIIQITKHGRSAAVLMSADDLDSLHETLFWLSQPGVREDVAAARQAVAEETTTSGE
GLRARYGLPPL

Download         Length: 276 bp

>AT173584 NZ_CP080247:3439309-3439683 [Escherichia sp. TM-G17TGC]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References