Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-PHD
Location 735538..736181 Replicon chromosome
Accession NZ_CP062221
Organism Cellulomonas palmilytica strain EW123

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag F1D97_RS03540 Protein ID WP_236122346.1
Coordinates 735798..736181 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag F1D97_RS03535 Protein ID WP_236122345.1
Coordinates 735538..735801 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1D97_RS03515 (F1D97_03470) 730568..730804 + 237 WP_013885186.1 30S ribosomal protein S18 -
F1D97_RS03520 (F1D97_03475) 730820..731269 + 450 WP_236122342.1 50S ribosomal protein L9 -
F1D97_RS03525 (F1D97_03480) 731451..732812 - 1362 WP_236122343.1 MATE family efflux transporter -
F1D97_RS03530 (F1D97_03485) 733104..735446 + 2343 WP_236122344.1 replicative DNA helicase -
F1D97_RS03535 (F1D97_03490) 735538..735801 + 264 WP_236122345.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F1D97_RS03540 (F1D97_03495) 735798..736181 + 384 WP_236122346.1 PIN domain-containing protein Toxin
F1D97_RS03545 (F1D97_03500) 736270..737394 + 1125 WP_236122347.1 N-acetyltransferase -
F1D97_RS03550 (F1D97_03505) 737399..738604 + 1206 WP_236122348.1 GNAT family N-acetyltransferase -
F1D97_RS03555 (F1D97_03510) 738694..739152 - 459 WP_236122349.1 hypothetical protein -
F1D97_RS03560 (F1D97_03515) 739189..740178 - 990 WP_236122350.1 DUF2332 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-111)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-40)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13175.16 Da        Isoelectric Point: 5.6845

>T173583 WP_236122346.1 NZ_CP062221:735798-736181 [Cellulomonas palmilytica]
VRLILDTNVLIDGLVPTGTADEAAISMASLAELRFGVLVARTPEIRSARMRVLSSAESALAALPIDDAVASSYALLATKT
VGAGRQPRARAFDLLIAATAHAHGAALVTRNLGDFTGLDDVLEVRAP

Download         Length: 384 bp

>T173583 NZ_CP080247:2658265-2658372 [Escherichia sp. TM-G17TGC]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9551.70 Da        Isoelectric Point: 4.8007

>AT173583 WP_236122345.1 NZ_CP062221:735538-735801 [Cellulomonas palmilytica]
MTTVGVRELRQDASGVLRRVEQGERVVVTVHGRPVADIVPHTESRPTWRPVADLAAIFPGVDDPHWDEDMALVDGAATDP
FERGARP

Download         Length: 264 bp

>AT173583 NZ_CP080247:c2658215-2658152 [Escherichia sp. TM-G17TGC]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References