Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2124192..2124463 Replicon chromosome
Accession NZ_CP062204
Organism Escherichia coli strain C311

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2124322..2124425 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2124192..2124463 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IG172_RS10385 2120747..2121409 - 663 WP_000944256.1 exodeoxyribonuclease X -
IG172_RS10390 2121433..2122089 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
IG172_RS10395 2122191..2122421 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IG172_RS10400 2122560..2122934 + 375 WP_000204699.1 CopC domain-containing protein YobA -
IG172_RS10405 2122938..2123810 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
IG172_RS10410 2123823..2124164 + 342 WP_000976492.1 YebY family protein -
- 2124192..2124463 - 272 - - Antitoxin
- 2124322..2124425 + 104 - - Toxin
IG172_RS10415 2124560..2125216 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
IG172_RS10420 2125217..2125408 - 192 WP_001296140.1 YebW family protein -
IG172_RS10425 2125513..2125749 - 237 WP_001295499.1 DUF1480 family protein -
IG172_RS10430 2125867..2127306 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T173506 NZ_CP062204:2124322-2124425 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT173506 NZ_CP062204:c2124463-2124192 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References