Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2170744..2171015 Replicon chromosome
Accession NZ_CP062203
Organism Escherichia coli strain K_EC180

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2170874..2170977 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2170744..2171015 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IGX36_RS10525 2167299..2167961 - 663 WP_000944256.1 exodeoxyribonuclease X -
IGX36_RS10530 2167985..2168641 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
IGX36_RS10535 2168743..2168973 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IGX36_RS10540 2169112..2169486 + 375 WP_000204705.1 CopC domain-containing protein YobA -
IGX36_RS10545 2169490..2170362 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
IGX36_RS10550 2170375..2170716 + 342 WP_000976472.1 YebY family protein -
- 2170744..2171015 - 272 - - Antitoxin
- 2170874..2170977 + 104 - - Toxin
IGX36_RS10555 2171112..2171768 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
IGX36_RS10560 2171769..2171960 - 192 WP_001296140.1 YebW family protein -
IGX36_RS10565 2172065..2172301 - 237 WP_001295499.1 DUF1480 family protein -
IGX36_RS10570 2172419..2173858 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T173481 NZ_CP062203:2170874-2170977 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT173481 NZ_CP062203:c2171015-2170744 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References