173468

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 378099..378468 Replicon chromosome
Accession NZ_CP062164
Organism Xanthomonas arboricola pv. corylina strain A7

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag ICA18_RS01610 Protein ID WP_016904515.1
Coordinates 378334..378468 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag ICA18_RS01605 Protein ID WP_006451340.1
Coordinates 378099..378251 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ICA18_RS01580 (ICA18_01580) 374164..374706 - 543 WP_016904520.1 GTPase -
ICA18_RS01585 (ICA18_01585) 374703..375620 - 918 WP_039814989.1 hypothetical protein -
ICA18_RS01590 (ICA18_01590) 375715..376074 - 360 WP_016904518.1 hypothetical protein -
ICA18_RS01595 (ICA18_01595) 376138..376590 - 453 WP_039512628.1 roadblock/LC7 domain-containing protein -
ICA18_RS01600 (ICA18_01600) 377066..377989 + 924 WP_039512664.1 arginase -
ICA18_RS01605 (ICA18_01605) 378099..378251 + 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
ICA18_RS01610 (ICA18_01610) 378334..378468 + 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
ICA18_RS01615 (ICA18_01615) 378719..378928 + 210 WP_039512625.1 CsbD family protein -
ICA18_RS01620 (ICA18_01620) 379110..380399 + 1290 WP_039814994.1 tryptophan--tRNA ligase -
ICA18_RS01625 (ICA18_01625) 380457..381401 + 945 WP_039512622.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T173468 WP_016904515.1 NZ_CP062164:378334-378468 [Xanthomonas arboricola pv. corylina]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T173468 NZ_CP080223:2099002-2099105 [Escherichia coli O141:H4]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT173468 WP_006451340.1 NZ_CP062164:378099-378251 [Xanthomonas arboricola pv. corylina]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT173468 NZ_CP080223:c2099143-2098872 [Escherichia coli O141:H4]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References