Detailed information of TA system TA173425

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 3658167..3658510
• Replicon: chromosome
• Accession: NZ_CP062156
• Organism: Stenotrophomonas sp. CW117

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: -
• Locus tag: H7691_RS17025
• Protein ID: WP_056932450.1
• Coordinates: 3658167..3658301 (-)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: H7691_RS17030
• Protein ID: WP_056932451.1
• Coordinates: 3658358..3658510 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H7691_RS17000	3654024..3655022	-	999	WP_182212680.1	MBL fold metallo-hydrolase	-
H7691_RS17005	3655148..3655447	-	300	WP_182212679.1	hypothetical protein	-
H7691_RS17010	3655490..3656782	-	1293	WP_182212678.1	tryptophan--tRNA ligase	-
H7691_RS17015	3656892..3657674	+	783	WP_056932449.1	hypothetical protein	-
H7691_RS17020	3657753..3657974	-	222	WP_054667983.1	CsbD family protein	-
H7691_RS17025	3658167..3658301	-	135	WP_056932450.1	entericidin A/B family lipoprotein	Toxin
H7691_RS17030	3658358..3658510	-	153	WP_056932451.1	entericidin A/B family lipoprotein	Antitoxin
H7691_RS17035	3658638..3659558	-	921	WP_056932452.1	arginase	-
H7691_RS17040	3659773..3661170	+	1398	WP_056932453.1	oxygen-independent coproporphyrinogen III oxidase	-
H7691_RS17045	3661190..3661945	+	756	WP_056932454.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4596.46 Da
• Isoelectric Point: 10.2040

>T173425 WP_056932450.1 NZ_CP062156:c3658301-3658167 [Stenotrophomonas sp. CW117]
MKRTVALMMLSLFSIAVLSGCNTVAGAGKDVQKAGEKVEDAAKR

Nucleotide

• Length: 135 bp

>T173425 NZ_CP080172:c993770-993228 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5201.13 Da
• Isoelectric Point: 7.7213

>AT173425 WP_056932451.1 NZ_CP062156:c3658510-3658358 [Stenotrophomonas sp. CW117]
MKRVLMLALLAVFSAGMLSACNTVAGAGKDMQKAGEKVEDKAHDCSDGKC

Nucleotide

• Length: 153 bp

>AT173425 NZ_CP080172:c994065-993754 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACCAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA