Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3513432..3514132 Replicon chromosome
Accession NZ_CP062156
Organism Stenotrophomonas sp. CW117

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H7691_RS16275 Protein ID WP_056932487.1
Coordinates 3513704..3514132 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H7691_RS16270 Protein ID WP_056932491.1
Coordinates 3513432..3513704 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7691_RS16255 3509275..3509793 + 519 WP_182212701.1 hypothetical protein -
H7691_RS16260 3509954..3510508 + 555 WP_182212700.1 queuosine precursor transporter -
H7691_RS16265 3510533..3513352 - 2820 WP_056932488.1 bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase -
H7691_RS16270 3513432..3513704 + 273 WP_056932491.1 hypothetical protein Antitoxin
H7691_RS16275 3513704..3514132 + 429 WP_056932487.1 hypothetical protein Toxin
H7691_RS16280 3514437..3515951 + 1515 WP_056932486.1 acetyl-CoA hydrolase/transferase family protein -
H7691_RS16285 3516021..3516359 - 339 WP_054667735.1 YegP family protein -
H7691_RS16290 3516492..3516752 - 261 WP_054667736.1 GIY-YIG nuclease family protein -
H7691_RS16295 3516771..3517214 - 444 WP_152985094.1 hypothetical protein -
H7691_RS16300 3517362..3518435 - 1074 WP_056932484.1 3-deoxy-7-phosphoheptulonate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-141)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15875.31 Da        Isoelectric Point: 9.6599

>T173424 WP_056932487.1 NZ_CP062156:3513704-3514132 [Stenotrophomonas sp. CW117]
MRALLDVNVLIALHDSDHVHHHPASAWLRTHIAHGWASCPLTQNGCLRIMSQPGYAKPQPLASLVSMLARSTSTRFHAFW
PDAISVLDRTHFHHGYIHSPRQLTYLYLLALAVHHGGRLVTFDRHIALSAVAGARPEHLVQL

Download         Length: 429 bp

>T173424 NZ_CP080172:c847628-847350 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9861.07 Da        Isoelectric Point: 4.6509

>AT173424 WP_056932491.1 NZ_CP062156:3513432-3513704 [Stenotrophomonas sp. CW117]
INHQGEPHAPSLDIADDVLFAAKELARREKKPLGQVISELARRAFAQSDAPWDTTGVAEPLADYGIHPLPPRGVVVSNEL
IDRLRDEEGI

Download         Length: 273 bp

>AT173424 NZ_CP080172:c847891-847631 [Escherichia coli]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References