Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 2235069..2235597 Replicon chromosome
Accession NZ_CP062062
Organism Janthinobacterium sp. HH102

Toxin (Protein)


Gene name parE Uniprot ID A0A853STB8
Locus tag JAB4_RS10195 Protein ID WP_070224899.1
Coordinates 2235069..2235359 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A853STY9
Locus tag JAB4_RS10200 Protein ID WP_070224900.1
Coordinates 2235352..2235597 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JAB4_RS10170 2230961..2232073 + 1113 WP_070224896.1 AI-2E family transporter -
JAB4_RS10175 2232181..2232405 - 225 WP_010396348.1 hypothetical protein -
JAB4_RS10180 2232571..2233305 + 735 WP_070224897.1 phosphatase PAP2 family protein -
JAB4_RS10185 2233317..2234225 + 909 WP_139143795.1 diacylglycerol kinase family lipid kinase -
JAB4_RS10190 2234235..2235053 + 819 WP_070224898.1 metallophosphoesterase -
JAB4_RS10195 2235069..2235359 - 291 WP_070224899.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JAB4_RS10200 2235352..2235597 - 246 WP_070224900.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
JAB4_RS10205 2235694..2237085 - 1392 WP_070224901.1 cardiolipin synthase -
JAB4_RS10210 2237082..2239193 - 2112 WP_070225020.1 site-specific recombinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(7-76)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11246.85 Da        Isoelectric Point: 8.8795

>T173367 WP_070224899.1 NZ_CP062062:c2235359-2235069 [Janthinobacterium sp. HH102]
MAEYRLTPATEHDLEAIWAYTSQRWSVQQASLYLDNMTAAFDDLARAPETAPACEQIRPGYRRRKVGRHMIYFRITHYGI
AIVRILHDRMDAARHL

Download         Length: 291 bp

>T173367 NZ_CP080155:c944769-944455 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAATCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTCGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCCGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9193.21 Da        Isoelectric Point: 4.8232

>AT173367 WP_070224900.1 NZ_CP062062:c2235597-2235352 [Janthinobacterium sp. HH102]
MGTVRKTITLTDQQDDWIKAQIDAGRYTNDSEYIRDLIRREQERSAELDAIRAALVEGEASGEPQPFDARAFKQRMLAAH
G

Download         Length: 246 bp

>AT173367 NZ_CP080155:c944458-944042 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACGCCCAGGCGCTGGAACTGGTCGATCATCTGCTGCTCAACGATCCTGAAAATCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCTGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTTCCGGAAATTGGCAGTAAATCCATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAACTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A853STB8

Antitoxin

Source ID Structure
AlphaFold DB A0A853STY9

References