Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1912164..1912309 Replicon chromosome
Accession NZ_CP061975
Organism Klebsiella pneumoniae strain IR5086

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1912200..1912302 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1912164..1912309 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4I67_RS09280 1907294..1909354 + 2061 WP_004151449.1 oligopeptidase B -
H4I67_RS09285 1909358..1910017 - 660 WP_002911407.1 exodeoxyribonuclease X -
H4I67_RS09290 1910096..1910326 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H4I67_RS09295 1910439..1910813 + 375 WP_039819395.1 CopC domain-containing protein YobA -
H4I67_RS09300 1910817..1911686 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
H4I67_RS09305 1911703..1912041 + 339 WP_002911404.1 YebY family protein -
- 1912164..1912309 - 146 - - Antitoxin
- 1912200..1912302 + 103 - - Toxin
H4I67_RS09310 1912678..1912821 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
H4I67_RS09315 1912926..1913894 - 969 WP_014907334.1 VirK/YbjX family protein -
H4I67_RS09320 1914051..1914704 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
H4I67_RS09325 1914701..1914892 - 192 WP_002911395.1 YebW family protein -
H4I67_RS09330 1914990..1915229 - 240 WP_002911393.1 YebV family protein -
H4I67_RS09335 1915345..1916778 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T173340 NZ_CP061975:1912200-1912302 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT173340 NZ_CP061975:c1912309-1912164 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References