Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1986436..1986581 Replicon chromosome
Accession NZ_CP061970
Organism Klebsiella pneumoniae strain IR5755

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1986472..1986574 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1986436..1986581 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4I70_RS09595 1981566..1983626 + 2061 WP_047694778.1 oligopeptidase B -
H4I70_RS09600 1983630..1984289 - 660 WP_102000926.1 exodeoxyribonuclease X -
H4I70_RS09605 1984368..1984598 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H4I70_RS09610 1984711..1985085 + 375 WP_023285314.1 CopC domain-containing protein YobA -
H4I70_RS09615 1985089..1985958 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
H4I70_RS09620 1985975..1986313 + 339 WP_002911404.1 YebY family protein -
- 1986436..1986581 - 146 - - Antitoxin
- 1986472..1986574 + 103 - - Toxin
H4I70_RS09625 1986949..1987092 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
H4I70_RS09630 1987197..1988165 - 969 WP_004151446.1 VirK/YbjX family protein -
H4I70_RS09635 1988322..1988975 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
H4I70_RS09640 1988972..1989163 - 192 WP_002911395.1 YebW family protein -
H4I70_RS09645 1989261..1989500 - 240 WP_002911393.1 YebV family protein -
H4I70_RS09650 1989616..1991049 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T173321 NZ_CP061970:1986472-1986574 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT173321 NZ_CP061970:c1986581-1986436 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References