Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1909877..1910022 Replicon chromosome
Accession NZ_CP061948
Organism Klebsiella pneumoniae strain IR5065

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1909913..1910015 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1909877..1910022 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4I82_RS09425 1905007..1907067 + 2061 WP_004151449.1 oligopeptidase B -
H4I82_RS09430 1907071..1907730 - 660 WP_032425085.1 exodeoxyribonuclease X -
H4I82_RS09435 1907809..1908039 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H4I82_RS09440 1908152..1908526 + 375 WP_004151448.1 CopC domain-containing protein YobA -
H4I82_RS09445 1908530..1909399 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
H4I82_RS09450 1909416..1909754 + 339 WP_016529031.1 YebY family protein -
- 1909877..1910022 - 146 - - Antitoxin
- 1909913..1910015 + 103 - - Toxin
H4I82_RS09455 1910390..1910533 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
H4I82_RS09460 1910638..1911606 - 969 WP_004151446.1 VirK/YbjX family protein -
H4I82_RS09465 1911763..1912416 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
H4I82_RS09470 1912413..1912604 - 192 WP_002911395.1 YebW family protein -
H4I82_RS09475 1912702..1912941 - 240 WP_002911393.1 YebV family protein -
H4I82_RS09480 1913057..1914490 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T173209 NZ_CP061948:1909913-1910015 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT173209 NZ_CP061948:c1910022-1909877 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References