Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relE/YoeB-RelB
Location 4225477..4226004 Replicon chromosome
Accession NZ_CP061947
Organism Algoriphagus sp. Y33

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag ID165_RS16905 Protein ID WP_192346273.1
Coordinates 4225750..4226004 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag ID165_RS16900 Protein ID WP_192346271.1
Coordinates 4225477..4225737 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ID165_RS16885 4221073..4222272 + 1200 WP_192351624.1 winged helix DNA-binding domain-containing protein -
ID165_RS16890 4222319..4222765 - 447 WP_192346267.1 hypothetical protein -
ID165_RS16895 4222937..4225390 + 2454 WP_192346269.1 ABC transporter permease -
ID165_RS16900 4225477..4225737 + 261 WP_192346271.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
ID165_RS16905 4225750..4226004 + 255 WP_192346273.1 Txe/YoeB family addiction module toxin Toxin
ID165_RS16910 4226432..4228138 - 1707 WP_192346275.1 lysine--tRNA ligase -
ID165_RS16915 4228212..4229399 - 1188 WP_192346277.1 proline dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10158.66 Da        Isoelectric Point: 9.8062

>T173206 WP_192346273.1 NZ_CP061947:4225750-4226004 [Algoriphagus sp. Y33]
MNIIFSNRAWEDYLYWNATDKKIFKKINSLIKECQRTPFSGIGKPEPLKHELSGAWSRRIDREHRLVYRVKDDPLEIAQC
RHHY

Download         Length: 255 bp

>T173206 NZ_CP080119:c3674982-3674875 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9886.02 Da        Isoelectric Point: 4.3217

>AT173206 WP_192346271.1 NZ_CP061947:4225477-4225737 [Algoriphagus sp. Y33]
MDVTTYSNFRQNLKSHLDDVVNDQKALYVTRANGEDVVVLSKSDYEGLQETYYLMRSPKNAERLMEALKELDEGGGIKRD
LIEIDE

Download         Length: 261 bp

>AT173206 NZ_CP080119:3675030-3675096 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References