Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 3294781..3296411 Replicon chromosome
Accession NZ_CP061947
Organism Algoriphagus sp. Y33

Toxin (Protein)


Gene name HipA3 Uniprot ID -
Locus tag ID165_RS13225 Protein ID WP_192085311.1
Coordinates 3294781..3296082 (-) Length 434 a.a.

Antitoxin (Protein)


Gene name HipB3 Uniprot ID -
Locus tag ID165_RS13230 Protein ID WP_192085312.1
Coordinates 3296076..3296411 (-) Length 112 a.a.

Genomic Context

ID165_RS13210ID165_RS13215ID165_RS13220ID165_RS13225ID165_RS13230ID165_RS13235ID165_RS13240
Location: 3291665..3292435 (771 bp)
Type: Others
Protein ID: WP_192085308.1
Location: 3292660..3293544 (885 bp)
Type: Others
Protein ID: WP_192085309.1
Location: 3293651..3294772 (1122 bp)
Type: Others
Protein ID: WP_192085310.1
Location: 3294781..3296082 (1302 bp)
Type: Toxin
Protein ID: WP_192085311.1
Location: 3296076..3296411 (336 bp)
Type: Antitoxin
Protein ID: WP_192085312.1
Location: 3296553..3300434 (3882 bp)
Type: Others
Protein ID: WP_192085313.1
Location: 3300435..3301256 (822 bp)
Type: Others
Protein ID: WP_192085314.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ID165_RS132103291665..3292435+771WP_192085308.1YdcF family protein-
ID165_RS132153292660..3293544+885WP_192085309.1DUF72 domain-containing protein-
ID165_RS132203293651..3294772+1122WP_192085310.1ATP-binding protein-
ID165_RS132253294781..3296082-1302WP_192085311.1type II toxin-antitoxin system HipA family toxinToxin
ID165_RS132303296076..3296411-336WP_192085312.1transcriptional regulatorAntitoxin
ID165_RS132353296553..3300434-3882WP_192085313.1DNA helicase-
ID165_RS132403300435..3301256-822WP_192085314.1SDR family oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(177-407)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-66)


Sequences

Toxin        


Download         Length: 434 a.a.        Molecular weight: 48743.69 Da        Isoelectric Point: 6.8273

>T173205 WP_192085311.1 NZ_CP061947:c3296082-3294781 [Algoriphagus sp. Y33]
MVVAAEIRIWDKLVGAVLWDDSEQLGSFEFHQDFLRSGLDISPVKMPLSQGNRVHAFPELRRARGDAFDTFKGLPGLLAD
MLPDKYGNQLINTWLIQNGRVADSLNPVEQLCFIGKRGVGALEIRPSLRDETIKASSIEIDSLVNIAGKILNSREDFQSN
LTGEERSALSDILKIGTSAGGARAKAVIAYNPKTGKVKSGQVKAPSGFSYWIIKFDGVHDSQFGSTLGYGRVEMAYFLMA
QSAGIEMSECRLFEENGRAHFMTKRFDRHDDGQKIHMQSLCGLRHFDFNQVGDYSYEQVFETMRMLRLSYPEAEQMFIRM
VFNVLARNCDDHTKNFAFLMDKDGKWKLSPAYDICYAYRPGSVWVSAQSLLVNGKREGIQHADFLEVAHKMNIKKPEEKI
DAVVTAIKKWKEFAEEAKVDSELRDGIASTLLV

Download         Length: 1302 bp

>T173205 NZ_CP080119:2823385-2823687 [Escherichia coli]
ATGGCTCAAAAGAAAAATATAAGGAGTTTTCGTGATGCCTGGTTGGCTGATTTTTTTGTCCATTCAACGCCACATCGAAA
GATCCCTGCTGAAATCCATACCACGTTATCACGAAAGTTGGACATCATTAATGCTGCCACTTCTCATCGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATTTTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTTTTTAGACCCACACAACTACTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12991.88 Da        Isoelectric Point: 10.2079

>AT173205 WP_192085312.1 NZ_CP061947:c3296411-3296076 [Algoriphagus sp. Y33]
MDYNQLSDTAILHQLGRFVKHHRMDQNKSQEQLATAAGISRSTLSLLERGEKVNLITLIQVLRVLDKLQWLESFEVKKTI
SPIDYIKLQKKHERQRIRNSDRAAENPPSEW

Download         Length: 336 bp

>AT173205 NZ_CP080119:2823723-2824064 [Escherichia coli]
ATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTTCTCTATGAATATCTGGAACCGCTCGATTTGAAAAT
CAATGAGTTAGCAGAGTTGCTGCATGTTCATCGTAATAGCGTCAGTGCACTGATCAATAACAATCGTAAACTCACCACTG
AGATGGCATTCCGTCTGGCGAAAGTTTTTGATACCACAGTCGATTTTTGGCTAAACCTCCAGGCGGCAGTTGATCTTTGG
GAAGTTGAAAACAACATGCGTACCCAGGAAGAATTGGGACGGATTGAAACAGTGGCTGAATATTTGGCACGCCGTGAAGA
GCGTGCAAAAAAGGTCGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References