Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 2487904..2488463 | Replicon | chromosome |
| Accession | NZ_CP061941 | ||
| Organism | Marinomonas algicola strain SM1966 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A120DEA8 |
| Locus tag | IEZ33_RS11465 | Protein ID | WP_046225271.1 |
| Coordinates | 2488185..2488463 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | IEZ33_RS11460 | Protein ID | WP_191600200.1 |
| Coordinates | 2487904..2488188 (+) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IEZ33_RS11425 | 2483635..2484354 | + | 720 | WP_191600195.1 | enoyl-CoA hydratase/isomerase family protein | - |
| IEZ33_RS11430 | 2484363..2484938 | + | 576 | WP_191600196.1 | cysteine dioxygenase | - |
| IEZ33_RS11435 | 2485653..2485841 | + | 189 | WP_191600197.1 | CsbD family protein | - |
| IEZ33_RS11440 | 2485904..2486062 | + | 159 | WP_191600198.1 | YqaE/Pmp3 family membrane protein | - |
| IEZ33_RS11445 | 2486242..2486808 | + | 567 | WP_206696846.1 | VTT domain-containing protein | - |
| IEZ33_RS11450 | 2487195..2487566 | - | 372 | Protein_2229 | IS110 family transposase | - |
| IEZ33_RS11455 | 2487545..2487751 | - | 207 | Protein_2230 | transposase | - |
| IEZ33_RS11460 | 2487904..2488188 | + | 285 | WP_191600200.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| IEZ33_RS11465 | 2488185..2488463 | + | 279 | WP_046225271.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| IEZ33_RS11470 | 2488565..2488873 | - | 309 | WP_191600201.1 | DUF1272 domain-containing protein | - |
| IEZ33_RS11475 | 2489190..2489645 | - | 456 | WP_191600202.1 | transposase | - |
| IEZ33_RS11480 | 2489744..2490091 | + | 348 | WP_191603617.1 | VTT domain-containing protein | - |
| IEZ33_RS11485 | 2490478..2490849 | - | 372 | Protein_2236 | IS110 family transposase | - |
| IEZ33_RS11490 | 2490828..2491034 | - | 207 | Protein_2237 | transposase | - |
| IEZ33_RS11495 | 2491187..2491471 | + | 285 | WP_191600200.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
| IEZ33_RS11500 | 2491468..2491746 | + | 279 | WP_046225271.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | - |
| IEZ33_RS11505 | 2491848..2492156 | - | 309 | WP_191600201.1 | DUF1272 domain-containing protein | - |
| IEZ33_RS11510 | 2492473..2492928 | - | 456 | WP_191600203.1 | transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10808.44 Da Isoelectric Point: 4.3324
>T173196 WP_046225271.1 NZ_CP061941:2488185-2488463 [Marinomonas algicola]
MILWEEESLNDREKIFEFLYDFNPDAADKTDEIIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSAIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAADKTDEIIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSAIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T173196 NZ_CP080119:1302563-1302940 [Escherichia coli]
ATGAACACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTCACGCTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTACGAACTGACCAGCCAGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA
ATGAACACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTCACGCTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTACGAACTGACCAGCCAGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10873.16 Da Isoelectric Point: 8.0515
>AT173196 WP_191600200.1 NZ_CP061941:2487904-2488188 [Marinomonas algicola]
MDTRIQFRVDDEIKRLAQQMAESQGRTLSDACRELTEQMAEQQRKALSHDAWLTEQVNLAFEKFDSGKSSFVDHDSAKAR
MAERKAKIRSRGQQ
MDTRIQFRVDDEIKRLAQQMAESQGRTLSDACRELTEQMAEQQRKALSHDAWLTEQVNLAFEKFDSGKSSFVDHDSAKAR
MAERKAKIRSRGQQ
Download Length: 285 bp
>AT173196 NZ_CP080119:1302105-1302473 [Escherichia coli]
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCGCCTCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGAAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGATGCAGATGCATACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCTGAAACGAAAAAGTAA
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCGCCTCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGAAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGATGCAGATGCATACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCTGAAACGAAAAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|