Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2188137..2188408 Replicon chromosome
Accession NZ_CP061914
Organism Escherichia coli strain SMBL

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2188267..2188370 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2188137..2188408 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IE857_RS10525 2184692..2185354 - 663 WP_000944256.1 exodeoxyribonuclease X -
IE857_RS10530 2185378..2186034 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
IE857_RS10535 2186136..2186366 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IE857_RS10540 2186505..2186879 + 375 WP_000204700.1 CopC domain-containing protein YobA -
IE857_RS10545 2186883..2187755 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
IE857_RS10550 2187768..2188109 + 342 WP_000976472.1 YebY family protein -
- 2188137..2188408 - 272 - - Antitoxin
- 2188267..2188370 + 104 - - Toxin
IE857_RS10555 2188505..2189161 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
IE857_RS10560 2189162..2189353 - 192 WP_001296140.1 YebW family protein -
IE857_RS10565 2189458..2189694 - 237 WP_001295499.1 DUF1480 family protein -
IE857_RS10570 2189812..2191251 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2091093..2204247 113154


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T173151 NZ_CP061914:2188267-2188370 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT173151 NZ_CP061914:c2188408-2188137 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References