Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/MazF(toxin) |
Location | 480100..480737 | Replicon | chromosome |
Accession | NZ_CP061853 | ||
Organism | Bacillus amyloliquefaciens strain MOH1-5b |
Toxin (Protein)
Gene name | mazF | Uniprot ID | G4NU33 |
Locus tag | BAMOH1_RS02410 | Protein ID | WP_003156187.1 |
Coordinates | 480387..480737 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | I2HMS5 |
Locus tag | BAMOH1_RS02405 | Protein ID | WP_003156188.1 |
Coordinates | 480100..480381 (+) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BAMOH1_RS02385 | 476465..477064 | - | 600 | WP_053573675.1 | rhomboid family intramembrane serine protease | - |
BAMOH1_RS02390 | 477157..477522 | + | 366 | WP_014304402.1 | holo-ACP synthase | - |
BAMOH1_RS02395 | 477687..478694 | + | 1008 | WP_007410230.1 | outer membrane lipoprotein carrier protein LolA | - |
BAMOH1_RS02400 | 478811..479980 | + | 1170 | WP_021495079.1 | alanine racemase | - |
BAMOH1_RS02405 | 480100..480381 | + | 282 | WP_003156188.1 | type II toxin-antitoxin system antitoxin EndoAI | Antitoxin |
BAMOH1_RS02410 | 480387..480737 | + | 351 | WP_003156187.1 | type II toxin-antitoxin system endoribonuclease NdoA | Toxin |
BAMOH1_RS02415 | 480855..481676 | + | 822 | WP_003156182.1 | STAS domain-containing protein | - |
BAMOH1_RS02420 | 481681..482046 | + | 366 | WP_007609584.1 | RsbT antagonist protein RsbS | - |
BAMOH1_RS02425 | 482049..482450 | + | 402 | WP_003156178.1 | anti-sigma regulatory factor | - |
BAMOH1_RS02430 | 482462..483469 | + | 1008 | WP_007609589.1 | PP2C family protein-serine/threonine phosphatase | - |
BAMOH1_RS02435 | 483533..483862 | + | 330 | WP_003156176.1 | anti-sigma factor antagonist RsbV | - |
BAMOH1_RS02440 | 483859..484341 | + | 483 | WP_007609591.1 | anti-sigma B factor RsbW | - |
BAMOH1_RS02445 | 484307..485095 | + | 789 | WP_029974100.1 | RNA polymerase sigma factor SigB | - |
BAMOH1_RS02450 | 485095..485697 | + | 603 | WP_128496463.1 | SpoIIE family protein phosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12977.98 Da Isoelectric Point: 4.8781
>T173124 WP_003156187.1 NZ_CP061853:480387-480737 [Bacillus amyloliquefaciens]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF
Download Length: 351 bp
>T173124 NZ_CP080116:c1413242-1412958 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGATAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAATGA
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGATAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAATGA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10562.92 Da Isoelectric Point: 6.4706
>AT173124 WP_003156188.1 NZ_CP061853:480100-480381 [Bacillus amyloliquefaciens]
MSESSARTEMKISLPENLVAELDGVAMREKRSRNELISQAVRAYVSERTTRHNRDLMRRGYMEMAKINLNISSEAHYAEC
EAETTVERLVSGG
MSESSARTEMKISLPENLVAELDGVAMREKRSRNELISQAVRAYVSERTTRHNRDLMRRGYMEMAKINLNISSEAHYAEC
EAETTVERLVSGG
Download Length: 282 bp
>AT173124 NZ_CP080116:c1413478-1413245 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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