Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE(toxin)
Location 4562514..4563067 Replicon chromosome
Accession NZ_CP061849
Organism Chromobacterium haemolyticum strain Bb2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IEZ30_RS21090 Protein ID WP_081575169.1
Coordinates 4562795..4563067 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A2T5NS08
Locus tag IEZ30_RS21085 Protein ID WP_019102024.1
Coordinates 4562514..4562798 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IEZ30_RS21060 4557635..4558714 + 1080 WP_019103142.1 ionic transporter y4hA -
IEZ30_RS21065 4558933..4559355 - 423 WP_052051917.1 nuclear transport factor 2 family protein -
IEZ30_RS21070 4559395..4560099 - 705 WP_191186049.1 DsbA family protein -
IEZ30_RS21075 4560282..4561163 - 882 WP_043589989.1 MBL fold metallo-hydrolase -
IEZ30_RS21080 4561292..4562206 + 915 WP_043589705.1 LysR family transcriptional regulator -
IEZ30_RS21085 4562514..4562798 + 285 WP_019102024.1 hypothetical protein Antitoxin
IEZ30_RS21090 4562795..4563067 + 273 WP_081575169.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
IEZ30_RS21095 4563595..4564044 + 450 WP_043589703.1 hypothetical protein -
IEZ30_RS21100 4564155..4565069 - 915 WP_198001611.1 LysR family transcriptional regulator -
IEZ30_RS21105 4565164..4566177 + 1014 WP_043589988.1 zinc-binding alcohol dehydrogenase family protein -
IEZ30_RS21110 4566751..4567443 + 693 WP_019102518.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10250.79 Da        Isoelectric Point: 6.7161

>T173112 WP_081575169.1 NZ_CP061849:4562795-4563067 [Chromobacterium haemolyticum]
MKLAWTPDAVADREAIFEYIAADNPAAALALDELFEQQASRLLLHPELGRAGRVAGTREWVLHRNYVCVYDLVTDQLRVL
RVLHVARQRP

Download         Length: 273 bp

>T173112 NZ_CP080107:c2928481-2928378 [Enterobacter asburiae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10962.27 Da        Isoelectric Point: 5.9110

>AT173112 WP_019102024.1 NZ_CP061849:4562514-4562798 [Chromobacterium haemolyticum]
MSESTFTFRVDESLKQEFAKVAKLQDRTGAQLLRDFMREVVRKNEEAAEYDQWFRSQVQQGLDQANAGELLPGDQVEAHF
AAKRAELRRRMAER

Download         Length: 285 bp

>AT173112 NZ_CP080107:2928372-2928516 [Enterobacter asburiae]
ACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2T5NS08

References