Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /RES-TIGR02293 |
Location | 1361173..1362056 | Replicon | chromosome |
Accession | NZ_CP061848 | ||
Organism | Pseudomonas asiatica strain C3 |
Toxin (Protein)
Gene name | - | Uniprot ID | A0A0C1HTG7 |
Locus tag | IE322_RS06290 | Protein ID | WP_015270851.1 |
Coordinates | 1361619..1362056 (+) | Length | 146 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | F8G488 |
Locus tag | IE322_RS06285 | Protein ID | WP_013973163.1 |
Coordinates | 1361173..1361622 (+) | Length | 150 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IE322_RS06260 | 1356541..1357740 | + | 1200 | WP_061304062.1 | sugar transporter | - |
IE322_RS06265 | 1357880..1358464 | - | 585 | WP_054572088.1 | LysE family translocator | - |
IE322_RS06270 | 1358515..1359345 | - | 831 | WP_015270854.1 | AraC family transcriptional regulator | - |
IE322_RS06275 | 1359393..1360316 | - | 924 | WP_054572087.1 | LysR family transcriptional regulator | - |
IE322_RS06280 | 1360421..1361074 | + | 654 | WP_054572086.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
IE322_RS06285 | 1361173..1361622 | + | 450 | WP_013973163.1 | DUF2384 domain-containing protein | Antitoxin |
IE322_RS06290 | 1361619..1362056 | + | 438 | WP_015270851.1 | RES family NAD+ phosphorylase | Toxin |
IE322_RS06295 | 1362064..1363218 | - | 1155 | WP_054572084.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
IE322_RS06300 | 1363390..1364316 | - | 927 | WP_015270849.1 | LysR family transcriptional regulator | - |
IE322_RS06305 | 1364457..1365686 | + | 1230 | WP_015270848.1 | acyl-CoA dehydrogenase | - |
IE322_RS06310 | 1365764..1366828 | - | 1065 | WP_015270847.1 | TerC family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 146 a.a. Molecular weight: 15969.19 Da Isoelectric Point: 5.1199
>T173108 WP_015270851.1 NZ_CP061848:1361619-1362056 [Pseudomonas asiatica]
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF
VILWRISAYADLSGTGGLRVSGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPTTMRLLRIELPDTVSQAQLPALQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF
Download Length: 438 bp
>T173108 NZ_CP080105:1943-2281 [Klebsiella quasipneumoniae]
GTGACGACATATTGTCCAGCCAGAGGCGATGTCATTCTTTTAGATTTTAACCCTCAATCAGGGCATGAGCAGGCAGGGAA
AAGGCCTGCTCTTGTCGTTTCTGATGATTTGTTTAACCAAGTCACTGGGTTTGCTGTTGTTTGCCCCATAACTAATCAGA
TAAAAGGGTACCCTTTTGAAGTTCCTGTTGATGGGACTACTAAAACAACAGGGGTTATCTTGGCTGATCAAGTGAAGTCT
TTAGACTGGAAGGCCAGAGCGGCACGTACTGTTGATAGCGTTTCCGGCGAGACAGTAACTACAGTTGTTGATATGGTTTC
AAAAATTATTAAAGCATAA
GTGACGACATATTGTCCAGCCAGAGGCGATGTCATTCTTTTAGATTTTAACCCTCAATCAGGGCATGAGCAGGCAGGGAA
AAGGCCTGCTCTTGTCGTTTCTGATGATTTGTTTAACCAAGTCACTGGGTTTGCTGTTGTTTGCCCCATAACTAATCAGA
TAAAAGGGTACCCTTTTGAAGTTCCTGTTGATGGGACTACTAAAACAACAGGGGTTATCTTGGCTGATCAAGTGAAGTCT
TTAGACTGGAAGGCCAGAGCGGCACGTACTGTTGATAGCGTTTCCGGCGAGACAGTAACTACAGTTGTTGATATGGTTTC
AAAAATTATTAAAGCATAA
Antitoxin
Download Length: 150 a.a. Molecular weight: 17004.59 Da Isoelectric Point: 6.3405
>AT173108 WP_013973163.1 NZ_CP061848:1361173-1361622 [Pseudomonas asiatica]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKTRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL
Download Length: 450 bp
>AT173108 NZ_CP080105:1716-1946 [Klebsiella quasipneumoniae]
ATGACTACGGCTATTGGTAAATGGGGTAATGGCGCTGCTTTGCGTATCCCGCAGCCGTTCATGAAGCAGCTTGGGCTTAG
TATCGGTGATGTTGTTAATTTCCGCGTCACTGAAAGGGATTTAGTAATTACTAAAGCTGGCCCGACGCTTGAAGAACTGC
TCGGACAGTGCACTGCAGAAAATCGCCATCACGAGTATCTATGTGACTCTCAAGGTAAGGAGATGCTGTGA
ATGACTACGGCTATTGGTAAATGGGGTAATGGCGCTGCTTTGCGTATCCCGCAGCCGTTCATGAAGCAGCTTGGGCTTAG
TATCGGTGATGTTGTTAATTTCCGCGTCACTGAAAGGGATTTAGTAATTACTAAAGCTGGCCCGACGCTTGAAGAACTGC
TCGGACAGTGCACTGCAGAAAATCGCCATCACGAGTATCTATGTGACTCTCAAGGTAAGGAGATGCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0C1HTG7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | F8G488 |