Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
Location | 1043661..1044700 | Replicon | chromosome |
Accession | NZ_CP061848 | ||
Organism | Pseudomonas asiatica strain C3 |
Toxin (Protein)
Gene name | PP_4152 | Uniprot ID | A0A2N5BP56 |
Locus tag | IE322_RS04630 | Protein ID | WP_015271072.1 |
Coordinates | 1043661..1044236 (-) | Length | 192 a.a. |
Antitoxin (Protein)
Gene name | PP_4151 | Uniprot ID | A0A2N5BP88 |
Locus tag | IE322_RS04635 | Protein ID | WP_015271071.1 |
Coordinates | 1044233..1044700 (-) | Length | 156 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IE322_RS04620 | 1039248..1040153 | - | 906 | WP_013973410.1 | LysR family transcriptional regulator | - |
IE322_RS04625 | 1040516..1043446 | - | 2931 | WP_137188394.1 | aminotransferase | - |
IE322_RS04630 | 1043661..1044236 | - | 576 | WP_015271072.1 | PIN domain-containing protein | Toxin |
IE322_RS04635 | 1044233..1044700 | - | 468 | WP_015271071.1 | helix-turn-helix domain-containing protein | Antitoxin |
IE322_RS04640 | 1044882..1045145 | - | 264 | WP_015271070.1 | DUF3077 domain-containing protein | - |
IE322_RS04645 | 1045302..1045544 | - | 243 | WP_015271069.1 | hypothetical protein | - |
IE322_RS04650 | 1046251..1047864 | - | 1614 | WP_085720482.1 | ABC transporter ATP-binding protein | - |
IE322_RS04655 | 1047866..1048885 | - | 1020 | WP_013973404.1 | ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 1034265..1044700 | 10435 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21970.23 Da Isoelectric Point: 5.0798
>T173107 WP_015271072.1 NZ_CP061848:c1044236-1043661 [Pseudomonas asiatica]
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSTKIHDEWKRNLLLNRPDLTLEQVDRTSRRMDAAVPDALVTDY
ESLVEGLDLPDKDDRHVLAAAIKCNASVIVTFNLKDFPETALDVFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRMSLKN
PPHSVQQYLDRLLQQKLPESVKLLSEFKFLL
MKHSPFTAIYDANVLYPAPLRDFLMNLALTGIYRARWSTKIHDEWKRNLLLNRPDLTLEQVDRTSRRMDAAVPDALVTDY
ESLVEGLDLPDKDDRHVLAAAIKCNASVIVTFNLKDFPETALDVFDIEPLHPDDFIADLWDLDKAAVLEAAQRQRMSLKN
PPHSVQQYLDRLLQQKLPESVKLLSEFKFLL
Download Length: 576 bp
>T173107 NZ_CP080104:8165-8440 [Klebsiella quasipneumoniae]
TTGTCGAAGTGGAATATTAAGTTCACGAAGAATGGCGCTGATGATATCAATTACTGGCGTGGTACTGACAAAAAGAAGTT
TGAACGTATCCGGCAGCTACTTCACAGCATCGAGTCTGATCCGTTAACTGGTATAGGGAAGCCTGAGCGATTACGCCATC
ACAAAGATCCTGCGCTCTATTCTCGGCGTATCGATCAGAGCCATAGGCTTGTATATTCAATCCAAAACGGAGAAATTATC
ATCTACGCAGCGCGTTATCACTACGGCGATAAATAG
TTGTCGAAGTGGAATATTAAGTTCACGAAGAATGGCGCTGATGATATCAATTACTGGCGTGGTACTGACAAAAAGAAGTT
TGAACGTATCCGGCAGCTACTTCACAGCATCGAGTCTGATCCGTTAACTGGTATAGGGAAGCCTGAGCGATTACGCCATC
ACAAAGATCCTGCGCTCTATTCTCGGCGTATCGATCAGAGCCATAGGCTTGTATATTCAATCCAAAACGGAGAAATTATC
ATCTACGCAGCGCGTTATCACTACGGCGATAAATAG
Antitoxin
Download Length: 156 a.a. Molecular weight: 17366.86 Da Isoelectric Point: 5.3408
>AT173107 WP_015271071.1 NZ_CP061848:c1044700-1044233 [Pseudomonas asiatica]
MTTADLSRKMLPDEKEIAVAVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPYLVKLLDESVIPHTKTGRHRRVKFSDLVAYKDKRDEVSRAAMDALAAEAQELRMGYE
MTTADLSRKMLPDEKEIAVAVESSRTLAAFLSTKSDTQRIELLNEENQRQVVEVPTFALRLFGEILSELALGNSVKVVPI
HAELTTQEAADLLNVSRPYLVKLLDESVIPHTKTGRHRRVKFSDLVAYKDKRDEVSRAAMDALAAEAQELRMGYE
Download Length: 468 bp
>AT173107 NZ_CP080104:7939-8184 [Klebsiella quasipneumoniae]
ATGCATGCAATCACTTTTACGGATGCCCGTAAACATTTTGCCGATACCATGAAGCGTGTTACCGATGATGCTGAGCCAGT
ACGAGTAATGCGGCGAGATGCACCTGATATCGTCATGATCGATGCTGGAGAGTATGAGGCACTCATAGAAACAGTGTATC
TGTTCAGCAATCCTGCGAATGCTGCTCATATCAATGAGTCAATGAAACAGGCGGAGCGCGGCGAATTTGTCGAAGTGGAA
TATTAA
ATGCATGCAATCACTTTTACGGATGCCCGTAAACATTTTGCCGATACCATGAAGCGTGTTACCGATGATGCTGAGCCAGT
ACGAGTAATGCGGCGAGATGCACCTGATATCGTCATGATCGATGCTGGAGAGTATGAGGCACTCATAGAAACAGTGTATC
TGTTCAGCAATCCTGCGAATGCTGCTCATATCAATGAGTCAATGAAACAGGCGGAGCGCGGCGAATTTGTCGAAGTGGAA
TATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2N5BP56 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2N5BP88 |