Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1810374..1810519 Replicon chromosome
Accession NZ_CP061842
Organism Klebsiella pneumoniae strain HC139

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1810410..1810512 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1810374..1810519 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IEY90_RS08850 1805504..1807564 + 2061 WP_004151449.1 oligopeptidase B -
IEY90_RS08855 1807568..1808227 - 660 WP_002911407.1 exodeoxyribonuclease X -
IEY90_RS08860 1808306..1808536 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IEY90_RS08865 1808649..1809023 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IEY90_RS08870 1809027..1809896 + 870 WP_064148102.1 copper homeostasis membrane protein CopD -
IEY90_RS08875 1809913..1810251 + 339 WP_002911404.1 YebY family protein -
- 1810374..1810519 - 146 - - Antitoxin
- 1810410..1810512 + 103 - - Toxin
IEY90_RS08880 1810888..1811031 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IEY90_RS08885 1811136..1812104 - 969 WP_014907334.1 VirK/YbjX family protein -
IEY90_RS08890 1812261..1812914 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
IEY90_RS08895 1812911..1813102 - 192 WP_002911395.1 YebW family protein -
IEY90_RS08900 1813200..1813439 - 240 WP_002911393.1 YebV family protein -
IEY90_RS08905 1813555..1814988 - 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T173086 NZ_CP061842:1810410-1810512 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT173086 NZ_CP061842:c1810519-1810374 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References