Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2022071..2022216 | Replicon | chromosome |
| Accession | NZ_CP061832 | ||
| Organism | Klebsiella pneumoniae strain C0674 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2022107..2022209 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2022071..2022216 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IFX77_RS09820 | 2017201..2019261 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| IFX77_RS09825 | 2019265..2019924 | - | 660 | WP_080893182.1 | exodeoxyribonuclease X | - |
| IFX77_RS09830 | 2020003..2020233 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| IFX77_RS09835 | 2020346..2020720 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| IFX77_RS09840 | 2020724..2021593 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| IFX77_RS09845 | 2021610..2021948 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 2022071..2022216 | - | 146 | - | - | Antitoxin |
| - | 2022107..2022209 | + | 103 | - | - | Toxin |
| IFX77_RS09850 | 2022585..2022728 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| IFX77_RS09855 | 2022833..2023801 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| IFX77_RS09860 | 2023958..2024611 | + | 654 | WP_023280291.1 | protein-serine/threonine phosphatase | - |
| IFX77_RS09865 | 2024608..2024799 | - | 192 | WP_002911395.1 | YebW family protein | - |
| IFX77_RS09870 | 2024897..2025136 | - | 240 | WP_002911393.1 | YebV family protein | - |
| IFX77_RS09875 | 2025252..2026685 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T173062 NZ_CP061832:2022107-2022209 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT173062 NZ_CP061832:c2022216-2022071 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
