Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3651988..3652629 Replicon chromosome
Accession NZ_CP061828
Organism Acinetobacter seifertii strain AS42

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC779_RS17490 Protein ID WP_077168983.1
Coordinates 3651988..3652377 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC779_RS17495 Protein ID WP_151276929.1
Coordinates 3652384..3652629 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC779_RS17475 3647100..3649295 - 2196 WP_019457776.1 TRAP transporter large permease subunit -
IC779_RS17480 3649483..3650049 - 567 WP_004705397.1 rhombosortase -
IC779_RS17485 3650134..3651219 - 1086 WP_019457778.1 hypothetical protein -
IC779_RS17490 3651988..3652377 - 390 WP_077168983.1 hypothetical protein Toxin
IC779_RS17495 3652384..3652629 - 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC779_RS17500 3652831..3654003 + 1173 WP_077168982.1 acyl-CoA dehydrogenase family protein -
IC779_RS17505 3654053..3655542 - 1490 Protein_3416 NAD(P)/FAD-dependent oxidoreductase -
IC779_RS17510 3655724..3656101 - 378 WP_002049717.1 50S ribosomal protein L17 -
IC779_RS17515 3656120..3657127 - 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15626.79 Da        Isoelectric Point: 9.8344

>T173057 WP_077168983.1 NZ_CP061828:c3652377-3651988 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T173057 NZ_CP080085:c4156750-4156208 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT173057 WP_151276929.1 NZ_CP061828:c3652629-3652384 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT173057 NZ_CP080085:c4157045-4156734 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACTAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References