Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3803258..3803915 Replicon chromosome
Accession NZ_CP061801
Organism Enterobacter mori strain HSW1412

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IDM36_RS18110 Protein ID WP_182272555.1
Coordinates 3803258..3803668 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IDM36_RS18115 Protein ID WP_182272556.1
Coordinates 3803649..3803915 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IDM36_RS18090 3799250..3800983 - 1734 WP_196390447.1 single-stranded-DNA-specific exonuclease RecJ -
IDM36_RS18095 3800989..3801702 - 714 WP_182272552.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
IDM36_RS18100 3801731..3802627 - 897 WP_196390448.1 site-specific tyrosine recombinase XerD -
IDM36_RS18105 3802729..3803250 + 522 WP_196390449.1 flavodoxin FldB -
IDM36_RS18110 3803258..3803668 - 411 WP_182272555.1 protein YgfX Toxin
IDM36_RS18115 3803649..3803915 - 267 WP_182272556.1 FAD assembly factor SdhE Antitoxin
IDM36_RS18120 3804211..3805191 + 981 WP_182272557.1 tRNA-modifying protein YgfZ -
IDM36_RS18125 3805299..3805958 - 660 WP_182272558.1 hemolysin III family protein -
IDM36_RS18130 3806124..3806435 - 312 WP_182272559.1 N(4)-acetylcytidine aminohydrolase -
IDM36_RS18135 3806487..3807218 + 732 WP_182274570.1 MurR/RpiR family transcriptional regulator -
IDM36_RS18140 3807335..3808768 + 1434 WP_196390450.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16195.12 Da        Isoelectric Point: 10.9455

>T173047 WP_182272555.1 NZ_CP061801:c3803668-3803258 [Enterobacter mori]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFILLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINACQGEIKLLMDSRLRWQGK
DWDIIGMPWMLNSGMMLRLRKVDGGRRQHLWLSADSMDTAEWRDLRRMILQQPTQE

Download         Length: 411 bp

>T173047 NZ_CP080085:c2262596-2262300 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCACTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10483.90 Da        Isoelectric Point: 4.8310

>AT173047 WP_182272556.1 NZ_CP061801:c3803915-3803649 [Enterobacter mori]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGQPADTGLQRMVELIQTRN
RERGPVAI

Download         Length: 267 bp

>AT173047 NZ_CP080085:c2262298-2261903 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References