Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 3538830..3539514 Replicon chromosome
Accession NZ_CP061801
Organism Enterobacter mori strain HSW1412

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag IDM36_RS16890 Protein ID WP_181522519.1
Coordinates 3539191..3539514 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag IDM36_RS16885 Protein ID WP_196390393.1
Coordinates 3538830..3539153 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IDM36_RS16855 3535008..3535277 + 270 WP_196390387.1 metal-sensing transcriptional repressor -
IDM36_RS16860 3535290..3536432 + 1143 WP_196390388.1 nickel/cobalt efflux protein RcnA -
IDM36_RS16865 3536602..3537030 + 429 WP_196390389.1 NirD/YgiW/YdeI family stress tolerance protein -
IDM36_RS16870 3537254..3538072 + 819 WP_196390390.1 DUF945 domain-containing protein -
IDM36_RS16875 3538105..3538578 + 474 WP_196390391.1 DNA repair protein RadC -
IDM36_RS16880 3538587..3538808 + 222 WP_196390392.1 DUF987 family protein -
IDM36_RS16885 3538830..3539153 + 324 WP_196390393.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
IDM36_RS16890 3539191..3539514 + 324 WP_181522519.1 TA system toxin CbtA family protein Toxin
IDM36_RS16895 3540428..3540601 - 174 WP_196390394.1 EAL domain-containing protein -
IDM36_RS16900 3540623..3541320 - 698 Protein_3303 IS1 family transposase -
IDM36_RS16905 3541349..3542725 - 1377 WP_196390395.1 EAL domain-containing protein -
IDM36_RS16910 3542838..3543428 - 591 WP_196390396.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(10-106)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12137.81 Da        Isoelectric Point: 5.5881

>T173045 WP_181522519.1 NZ_CP061801:3539191-3539514 [Enterobacter mori]
ISSVPATVPVSSRLSPVQVWQQLLTYLLEQHYGLTLNDTPFHDDTAIEEHIDAGITLADAVNFLVEKYELVRIDRKGFSW
QEQTPYISVVDILRARRSTGLLKTNVK

Download         Length: 324 bp

>T173045 NZ_CP080085:c2003498-2003163 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11969.71 Da        Isoelectric Point: 7.0268

>AT173045 WP_196390393.1 NZ_CP061801:3538830-3539153 [Enterobacter mori]
MQNSWGLKRDISPCFGARLVQEGCRLHFLADRAGISGTFNKDEALRLDQAFPLVMKQLELMLTTGELNLRHQHCVTLHHN
GLTCEADTLGSHGYVYIVIYPQASATQ

Download         Length: 324 bp

>AT173045 NZ_CP080085:c2003746-2003498 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References