Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1604162..1605075 Replicon chromosome
Accession NZ_CP061801
Organism Enterobacter mori strain HSW1412

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag IDM36_RS07570 Protein ID WP_182274366.1
Coordinates 1604162..1604635 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag IDM36_RS07575 Protein ID WP_182919707.1
Coordinates 1604632..1605075 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IDM36_RS07545 1599462..1599683 - 222 WP_008499993.1 cold shock-like protein CspD -
IDM36_RS07550 1599951..1600271 + 321 WP_182274362.1 ATP-dependent Clp protease adapter ClpS -
IDM36_RS07555 1600299..1602578 + 2280 WP_182274363.1 ATP-dependent Clp protease ATP-binding subunit ClpA -
IDM36_RS07560 1603036..1603473 + 438 WP_196391068.1 hypothetical protein -
IDM36_RS07565 1603636..1604061 + 426 WP_182274365.1 DUF3828 domain-containing protein -
IDM36_RS07570 1604162..1604635 - 474 WP_182274366.1 RES domain-containing protein Toxin
IDM36_RS07575 1604632..1605075 - 444 WP_182919707.1 DUF2384 domain-containing protein Antitoxin
IDM36_RS07580 1605257..1605475 - 219 WP_002211347.1 translation initiation factor IF-1 -
IDM36_RS07585 1605760..1606464 - 705 WP_182274368.1 leucyl/phenylalanyl-tRNA--protein transferase -
IDM36_RS07590 1606511..1608232 - 1722 WP_196391069.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
IDM36_RS07595 1608232..1609998 - 1767 WP_196391070.1 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(95-144)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17524.75 Da        Isoelectric Point: 5.0911

>T173034 WP_182274366.1 NZ_CP061801:c1604635-1604162 [Enterobacter mori]
MIFYRLVTGRYASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLAALEILVHVKRDTVLNQYQLFSIDIPDDQIDHLDKE
WLPGDWQENPAPVSTMDLGTSWLQASDALALILPSCIIPYENNAILNPLNPAFQQALSSVQRHSFVFDTRLAEKTAP

Download         Length: 474 bp

>T173034 NZ_CP080081:100262-100543 [Escherichia coli]
ATGACCTATGAACTGGCTTTTGACCGTAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAACTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGTCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATACCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCCGTTGGAAGA
AGGGAAAGCAGCGAAGTCTATCAGATCGCAGATTTGCGCTAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16347.66 Da        Isoelectric Point: 7.2059

>AT173034 WP_182919707.1 NZ_CP061801:c1605075-1604632 [Enterobacter mori]
MRTWVPAQKPADNALWRFAGLPANRGMRLIEYLNQGLPVSVLDNIHEWTAMSKADILRVTGINERNVARRKSAGRTLTPD
ESERVARFVRVLDTAVDYFGSKDEAWNWLQSPVRGLGNIAPVDLIATETGALEVTDLIGRLEHGVLA

Download         Length: 444 bp

>AT173034 NZ_CP080081:100021-100272 [Escherichia coli]
ATGAGCTATCAAATTCTGACAACTACAGCGGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACCGTAGCTGAAGG
TGAAGGGGACGCTGTTGCGATCCTGAACCGAAACGAACCGGCGTTCTATTGCGTTCCACCAAAACTTTACGCCTACTATC
GGGAACTCGCTGAAGATGCTGAGTTAAACGCTGTTGCTGATGAGCGCATGAAAAACCCGGAAATTGTGAAGGTTAACCTG
GATGACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References