Detailed information of TA system TA173032

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 543458..543974
• Replicon: chromosome
• Accession: NZ_CP061801
• Organism: Enterobacter mori strain HSW1412

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: IDM36_RS02635
• Protein ID: WP_182919309.1
• Coordinates: 543690..543974 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: IDM36_RS02630
• Protein ID: WP_182919308.1
• Coordinates: 543458..543700 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IDM36_RS02620	540338..541450	+	1113	WP_196391343.1	lactonase family protein	-
IDM36_RS02625	541470..543380	+	1911	WP_196390738.1	BglG family transcription antiterminator	-
IDM36_RS02630	543458..543700	+	243	WP_182919308.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
IDM36_RS02635	543690..543974	+	285	WP_182919309.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IDM36_RS02640	543978..544442	-	465	WP_196390739.1	anaerobic ribonucleoside-triphosphate reductase-activating protein	-
IDM36_RS02645	544443..544757	-	315	WP_196390740.1	hypothetical protein	-
IDM36_RS02650	544796..546934	-	2139	WP_182919311.1	anaerobic ribonucleoside-triphosphate reductase	-
IDM36_RS02655	547325..547906	-	582	WP_182919312.1	fructose PTS transporter subunit IIA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-69)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10949.78 Da
• Isoelectric Point: 9.6413

>T173032 WP_182919309.1 NZ_CP061801:543690-543974 [Enterobacter mori]
MTYELEFDPGALKEWHKLGDTVKTQFKKKLVDVLVDPRIESARLHGLHDCYKIKLKSSGYRLVYQVRDEVVMVFVVAIGK
REKSAVYHDADKRL

Nucleotide

• Length: 285 bp

>T173032 NZ_CP080080:c3927656-3927369 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8942.34 Da
• Isoelectric Point: 5.0651

>AT173032 WP_182919308.1 NZ_CP061801:543458-543700 [Enterobacter mori]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDGEDALIQTVRERLANPQKGIKVSLDDL

Nucleotide

• Length: 243 bp

>AT173032 NZ_CP080080:c3927382-3927080 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGACGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA