Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1095708..1096350 Replicon chromosome
Accession NZ_CP061799
Organism Desulfonema limicola strain 5ac10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag dnl_RS04575 Protein ID WP_207690587.1
Coordinates 1095916..1096350 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag dnl_RS04570 Protein ID WP_207690586.1
Coordinates 1095708..1095926 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
dnl_RS04565 (dnl_09950) 1091452..1095366 + 3915 WP_207690585.1 hypothetical protein -
dnl_RS04570 (dnl_09970) 1095708..1095926 + 219 WP_207690586.1 hypothetical protein Antitoxin
dnl_RS04575 (dnl_09980) 1095916..1096350 + 435 WP_207690587.1 putative toxin-antitoxin system toxin component, PIN family Toxin
dnl_RS04580 (dnl_10000) 1096750..1097259 - 510 WP_207690588.1 hypothetical protein -
dnl_RS04585 (dnl_10010) 1097259..1097549 - 291 WP_207690589.1 hypothetical protein -
dnl_RS04590 (dnl_10020) 1097549..1097917 - 369 WP_207690590.1 hypothetical protein -
dnl_RS04595 (dnl_10030) 1097910..1098857 - 948 WP_207690591.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 16554.07 Da        Isoelectric Point: 4.3088

>T173009 WP_207690587.1 NZ_CP061799:1095916-1096350 [Desulfonema limicola]
VENNIRVVIDTNIWISFLIGKMLSGLSEAIINDKIIILFSVELFEELIEVLNRPKFQKYFSNDDIAELISLLHLKTEQVE
VTEKFKDCRDPKDNFLLDLCVSGKADYLVTGDDDLLALNPFHGVEVTNYRSFQDILQNIVLKFS

Download         Length: 435 bp

>T173009 NZ_CP080075:2593295-2593402 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8458.88 Da        Isoelectric Point: 7.9715

>AT173009 WP_207690586.1 NZ_CP061799:1095708-1095926 [Desulfonema limicola]
MPYSLSINFNQLKSLIIQCGIEEKVEIIRMLEQDTLPIRFKRFLNKVKTNDLSIEEITAEVEAVREKRYSGK

Download         Length: 219 bp

>AT173009 NZ_CP080075:c2593245-2593182 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References