Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 657077..657719 Replicon chromosome
Accession NZ_CP061799
Organism Desulfonema limicola strain 5ac10

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag dnl_RS02755 Protein ID WP_207690245.1
Coordinates 657077..657511 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag dnl_RS02760 Protein ID WP_207690246.1
Coordinates 657501..657719 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
dnl_RS02740 (dnl_06000) 652150..653604 + 1455 WP_207690242.1 hypothetical protein -
dnl_RS02745 (dnl_06010) 653579..654616 + 1038 WP_207690243.1 hypothetical protein -
dnl_RS02750 (dnl_06020) 654643..656409 + 1767 WP_207690244.1 asparagine synthase-related protein -
dnl_RS02755 (dnl_06030) 657077..657511 - 435 WP_207690245.1 putative toxin-antitoxin system toxin component, PIN family Toxin
dnl_RS02760 (dnl_06040) 657501..657719 - 219 WP_207690246.1 hypothetical protein Antitoxin
dnl_RS02765 (dnl_06050) 657920..659431 + 1512 WP_207690247.1 ISKra4 family transposase -
dnl_RS02770 (dnl_06080) 660287..661405 + 1119 WP_207690248.1 site-specific integrase -
dnl_RS02775 (dnl_06090) 661521..662438 - 918 WP_207690249.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 16693.22 Da        Isoelectric Point: 4.2763

>T173008 WP_207690245.1 NZ_CP061799:c657511-657077 [Desulfonema limicola]
VENNIRVVIDTNIWISFLIGKMLSTLSDAIINDKIKILFSEELFEELIEVLNRPKFQKYFSQDDIAELISLLHLKTEQIE
ITEKFKDCRDPKDNFLLDLCVSGKADYLVTGDDDLLALNPFHGVEITNYRLFQDILQNLDLKLS

Download         Length: 435 bp

>T173008 NZ_CP080075:2592760-2592867 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8516.92 Da        Isoelectric Point: 6.9801

>AT173008 WP_207690246.1 NZ_CP061799:c657719-657501 [Desulfonema limicola]
MPYSLSINFNQLKSLIIQCGIEEKVEIIHMLERDTFPLRFKRFLNKIKSDELSLEEITAEVEAVREKRYSGK

Download         Length: 219 bp

>AT173008 NZ_CP080075:c2592707-2592646 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References