Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 6349403..6350661 | Replicon | chromosome |
| Accession | NZ_CP061778 | ||
| Organism | Pseudomonas aeruginosa strain ZBX-P13 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | V6AJ34 |
| Locus tag | IFJ79_RS29300 | Protein ID | WP_003086331.1 |
| Coordinates | 6349403..6350158 (-) | Length | 252 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | V6AJU7 |
| Locus tag | IFJ79_RS29305 | Protein ID | WP_003086329.1 |
| Coordinates | 6350293..6350661 (-) | Length | 123 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IFJ79_RS29290 (IFJ79_29295) | 6344574..6347117 | + | 2544 | WP_031686396.1 | acyl-homoserine-lactone acylase QuiP | - |
| IFJ79_RS29295 (IFJ79_29300) | 6347272..6348633 | - | 1362 | WP_073647918.1 | DNA recombination protein RmuC | - |
| IFJ79_RS29300 (IFJ79_29305) | 6349403..6350158 | - | 756 | WP_003086331.1 | RES family NAD+ phosphorylase | Toxin |
| IFJ79_RS29305 (IFJ79_29310) | 6350293..6350661 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
| IFJ79_RS29310 (IFJ79_29315) | 6350734..6352020 | - | 1287 | WP_031756378.1 | FAD-binding oxidoreductase | - |
| IFJ79_RS29315 (IFJ79_29320) | 6352076..6353569 | - | 1494 | WP_033990296.1 | aldehyde dehydrogenase family protein | - |
| IFJ79_RS29320 (IFJ79_29325) | 6353744..6354220 | + | 477 | WP_003086322.1 | hypothetical protein | - |
| IFJ79_RS29325 (IFJ79_29330) | 6354223..6354498 | - | 276 | WP_023098713.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28236.34 Da Isoelectric Point: 7.7294
>T172990 WP_003086331.1 NZ_CP061778:c6350158-6349403 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
>T172990 NZ_CP080070:2681090-2681197 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT172990 WP_003086329.1 NZ_CP061778:c6350661-6350293 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
>AT172990 NZ_CP080070:c2681043-2680977 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|