Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2162465..2162736 Replicon chromosome
Accession NZ_CP061764
Organism Escherichia coli O19:H7 strain 730V1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2162595..2162698 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2162465..2162736 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ID627_RS10545 2159020..2159682 - 663 WP_000944256.1 exodeoxyribonuclease X -
ID627_RS10550 2159706..2160362 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
ID627_RS10555 2160464..2160694 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ID627_RS10560 2160833..2161207 + 375 WP_000168738.1 CopC domain-containing protein YobA -
ID627_RS10565 2161211..2162083 + 873 WP_000879286.1 copper homeostasis membrane protein CopD -
ID627_RS10570 2162096..2162437 + 342 WP_000976472.1 YebY family protein -
- 2162465..2162736 - 272 - - Antitoxin
- 2162595..2162698 + 104 - - Toxin
ID627_RS10575 2162833..2163489 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
ID627_RS10580 2163490..2163681 - 192 WP_001313035.1 YebW family protein -
ID627_RS10585 2163786..2164022 - 237 WP_001295499.1 DUF1480 family protein -
ID627_RS10590 2164140..2165579 - 1440 WP_001383086.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172959 NZ_CP061764:2162595-2162698 [Escherichia coli O19:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT172959 NZ_CP061764:c2162736-2162465 [Escherichia coli O19:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References