Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2135838..2136109 Replicon chromosome
Accession NZ_CP061754
Organism Escherichia coli O18ac:H14 strain 873.10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2135968..2136071 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2135838..2136109 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IEC99_RS10325 2132393..2133055 - 663 WP_000944256.1 exodeoxyribonuclease X -
IEC99_RS10330 2133079..2133735 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
IEC99_RS10335 2133837..2134067 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IEC99_RS10340 2134206..2134580 + 375 WP_000168738.1 CopC domain-containing protein YobA -
IEC99_RS10345 2134584..2135456 + 873 WP_000879286.1 copper homeostasis membrane protein CopD -
IEC99_RS10350 2135469..2135810 + 342 WP_000976472.1 YebY family protein -
- 2135838..2136109 - 272 - - Antitoxin
- 2135968..2136071 + 104 - - Toxin
IEC99_RS10355 2136206..2136862 + 657 WP_057107450.1 protein-serine/threonine phosphatase -
IEC99_RS10360 2136863..2137054 - 192 WP_001313035.1 YebW family protein -
IEC99_RS10365 2137159..2137395 - 237 WP_001295499.1 DUF1480 family protein -
IEC99_RS10370 2137513..2138952 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172913 NZ_CP061754:2135968-2136071 [Escherichia coli O18ac:H14]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT172913 NZ_CP061754:c2136109-2135838 [Escherichia coli O18ac:H14]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References