Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 3578136..3578671 Replicon chromosome
Accession NZ_CP061725
Organism Micromonospora craniellae strain LHW63014

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ID554_RS15990 Protein ID WP_117229861.1
Coordinates 3578417..3578671 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag ID554_RS15985 Protein ID WP_117229862.1
Coordinates 3578136..3578420 (+) Length 95 a.a.

Genomic Context

ID554_RS15960ID554_RS15965ID554_RS15985ID554_RS15990ID554_RS15970ID554_RS15975ID554_RS15980ID554_RS15995ID554_RS16000ID554_RS16005
Location: 3575886..3576182 (297 bp)
Type: Others
Protein ID: WP_117229865.1
Location: 3576281..3576808 (528 bp)
Type: Others
Protein ID: WP_117229864.1
Location: 3578136..3578420 (285 bp)
Type: Antitoxin
Protein ID: WP_117229862.1
Location: 3578417..3578671 (255 bp)
Type: Toxin
Protein ID: WP_117229861.1
Location: 3576878..3577210 (333 bp)
Type: Others
Protein ID: WP_191088558.1
Location: 3577302..3577559 (258 bp)
Type: Others
Protein ID: WP_117229863.1
Location: 3577556..3577831 (276 bp)
Type: Others
Protein ID: WP_117229904.1
Location: 3578818..3579915 (1098 bp)
Type: Others
Protein ID: WP_117229860.1
Location: 3580161..3581618 (1458 bp)
Type: Others
Protein ID: WP_117229859.1
Location: 3581922..3582635 (714 bp)
Type: Others
Protein ID: WP_117229858.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ID554_RS159603575886..3576182+297WP_117229865.1DUF1540 domain-containing protein-
ID554_RS159653576281..3576808+528WP_117229864.1hypothetical protein-
ID554_RS159703576878..3577210-333WP_191088558.1hypothetical protein-
ID554_RS159753577302..3577559-258WP_117229863.1Txe/YoeB family addiction module toxin-
ID554_RS159803577556..3577831-276WP_117229904.1type II toxin-antitoxin system prevent-host-death family antitoxin-
ID554_RS159853578136..3578420+285WP_117229862.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
ID554_RS159903578417..3578671+255WP_117229861.1Txe/YoeB family addiction module toxinToxin
ID554_RS159953578818..3579915-1098WP_117229860.1integrase core domain-containing protein-
ID554_RS160003580161..3581618-1458WP_117229859.1plasmid pRiA4b ORF-3 family protein-
ID554_RS160053581922..3582635-714WP_117229858.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10236.56 Da        Isoelectric Point: 9.9424

>T172848 WP_117229861.1 NZ_CP061725:3578417-3578671 [Micromonospora craniellae]
VKVQFAGRGWEDYLTWQRDRQMLKRVNALIEDVRRNGHQGIGKPEQLRGNWAGFWSRRIDHEHRLVYRILDDTVQIAQCR
YHYE

Download         Length: 255 bp

>T172848 NZ_CP079991:c2944011-2943760 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10279.45 Da        Isoelectric Point: 4.3430

>AT172848 WP_117229862.1 NZ_CP061725:3578136-3578420 [Micromonospora craniellae]
MRTVPYSEVRQNLAKMLDHVVDDAEEVVVTRSGREAAVIISLREYESLKETAYLMASPANARRLNEAVEDLRNGGGEMRD
LIDPDASSGEASAA

Download         Length: 285 bp

>AT172848 NZ_CP079991:c2943763-2943509 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References