Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 66674..67239 Replicon chromosome
Accession NZ_CP061721
Organism Pseudarthrobacter sp. BIM B-2242

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IDT60_RS00310 Protein ID WP_191080430.1
Coordinates 66674..66967 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IDT60_RS00315 Protein ID WP_191080431.1
Coordinates 66964..67239 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IDT60_RS00295 62412..62702 - 291 WP_191080427.1 hypothetical protein -
IDT60_RS00300 62877..63770 - 894 WP_191080428.1 LysR family transcriptional regulator -
IDT60_RS00305 64314..66077 - 1764 WP_191080429.1 FAD-dependent oxidoreductase -
IDT60_RS00310 66674..66967 - 294 WP_191080430.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IDT60_RS00315 66964..67239 - 276 WP_191080431.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IDT60_RS00320 67352..67918 - 567 WP_191080432.1 recombinase family protein -
IDT60_RS00325 68059..68700 - 642 WP_191080433.1 hypothetical protein -
IDT60_RS00330 69107..69409 + 303 WP_191080434.1 DUF4193 domain-containing protein -
IDT60_RS00335 69581..69910 - 330 WP_191080435.1 hypothetical protein -
IDT60_RS00340 70178..71569 - 1392 WP_191080436.1 plasmid pRiA4b ORF-3 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 67352..67918 566


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11067.67 Da        Isoelectric Point: 10.1316

>T172841 WP_191080430.1 NZ_CP061721:c66967-66674 [Pseudarthrobacter sp. BIM B-2242]
VTDAQTAGHPSWKVEVTSPALKGFRRLPEKAAAAIVEFVTGVLADNPYRLSKPLTNELRGLRTARRGDYRVLFTLDVEEH
ILYVHRIEHRSDVYKPR

Download         Length: 294 bp

>T172841 NZ_CP079991:c2149231-2149124 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10169.35 Da        Isoelectric Point: 4.8784

>AT172841 WP_191080431.1 NZ_CP061721:c67239-66964 [Pseudarthrobacter sp. BIM B-2242]
MRTVPLSEAKDKLSALVEEADKTHEIIQITRHGHPSAVLMSAADLESLQETIHWLSQPGIREDLDQARRDIAEGNTTSGD
DLRREFGLPPR

Download         Length: 276 bp

>AT172841 NZ_CP079991:2149278-2149344 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References