Detailed information of TA system TA172840

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-TIGR02293
• Location: 2794655..2795568
• Replicon: chromosome
• Accession: NZ_CP061718
• Organism: Roseococcus sp. NIBR12

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: ICW72_RS13495
• Protein ID: WP_191083186.1
• Coordinates: 2795086..2795568 (+)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: ICW72_RS13490
• Protein ID: WP_191083185.1
• Coordinates: 2794655..2795089 (+)
• Length: 145 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICW72_RS13470	2789956..2791434	+	1479	WP_191083181.1	carboxypeptidase M32	-
ICW72_RS13475	2791449..2792126	-	678	WP_191083182.1	class I SAM-dependent methyltransferase	-
ICW72_RS13480	2792207..2792992	-	786	WP_191083183.1	creatininase family protein	-
ICW72_RS13485	2793059..2794591	+	1533	WP_191083184.1	deoxyribodipyrimidine photo-lyase	-
ICW72_RS13490	2794655..2795089	+	435	WP_191083185.1	DUF2384 domain-containing protein	Antitoxin
ICW72_RS13495	2795086..2795568	+	483	WP_191083186.1	RES family NAD+ phosphorylase	Toxin
ICW72_RS13505	2795696..2799685	-	3990	WP_191086259.1	AAA family ATPase	-
ICW72_RS13510	2799763..2800374	-	612	WP_191083187.1	thioredoxin domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (5-151)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (17-78)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 17141.53 Da
• Isoelectric Point: 9.0046

>T172840 WP_191083186.1 NZ_CP061718:2795086-2795568 [Roseococcus sp. NIBR12]
VSVTAWRIASDTRGWAADDLSGAGAEATGGRWNPPGQAVVYASMSRALACLETVVHLNAGGLPLNRYLVELTIPDALWKA
ARRETPESLPVGWDAEPASATSERLGGEWLAGGASALLLVPSVVVPEEWNLLLNPRHAGAAGVRARKVRKWLYDPRLRRA

Nucleotide

• Length: 483 bp

>T172840 NZ_CP079991:c2148696-2148589 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Protein

• Length: 145 a.a.
• Molecular weight: 15507.83 Da
• Isoelectric Point: 8.5251

>AT172840 WP_191083185.1 NZ_CP061718:2794655-2795089 [Roseococcus sp. NIBR12]
MSHASYAAIYDAPVTARIGRIRAGVPATTAKEWLDLPELGRNATLKALDLAIATFNRKVKERGTLSPAESERVLGLARLV
GQVESMVLEAGAPEGFDARAWLARWLQEPLPALGHARPLDFLNTMEGQRLVSDTLAKAISGAYA

Nucleotide

• Length: 435 bp

>AT172840 NZ_CP079991:2148743-2148809 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT