172836

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 304278..304870 Replicon chromosome
Accession NZ_CP061714
Organism Luteimonas sp. MC1825

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IDM46_RS01410 Protein ID WP_185114611.1
Coordinates 304574..304870 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IDM46_RS01405 Protein ID WP_185114610.1
Coordinates 304278..304571 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IDM46_RS01375 299654..300109 - 456 WP_185114605.1 hypothetical protein -
IDM46_RS01380 300389..300916 - 528 WP_185114606.1 GrpB family protein -
IDM46_RS01385 300935..301231 - 297 WP_185114607.1 DUF1294 domain-containing protein -
IDM46_RS01390 301339..301830 - 492 WP_185114608.1 cupin domain-containing protein -
IDM46_RS01395 302817..303119 - 303 WP_185115219.1 DUF2314 domain-containing protein -
IDM46_RS01400 303287..304105 - 819 WP_185114609.1 PDZ domain-containing protein -
IDM46_RS01405 304278..304571 - 294 WP_185114610.1 putative addiction module antidote protein Antitoxin
IDM46_RS01410 304574..304870 - 297 WP_185114611.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IDM46_RS01415 305087..305827 - 741 WP_185115220.1 endonuclease/exonuclease/phosphatase family protein -
IDM46_RS01420 305895..306737 - 843 WP_185114612.1 thiol:disulfide interchange protein DsbA/DsbL -
IDM46_RS01425 306771..307424 - 654 WP_185114613.1 thiol:disulfide interchange protein DsbA/DsbL -
IDM46_RS01430 307534..308463 - 930 WP_185114614.1 cytochrome c4 -
IDM46_RS01435 308624..309238 + 615 WP_185114615.1 ribosome biogenesis GTP-binding protein YihA/YsxC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-92)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11255.00 Da        Isoelectric Point: 10.1808

>T172836 WP_185114611.1 NZ_CP061714:c304870-304574 [Luteimonas sp. MC1825]
MVEILKSDTFDAWLRALRDRQAKARIEVRIRRLSLENPGQHRALKGGICELKIDHGPGYRVYYTFRNQTLVLLLCGGTKS
TQSQDIKLAQGIAKQWED

Download         Length: 297 bp

>T172836 NZ_CP079991:1144314-1144712 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10271.74 Da        Isoelectric Point: 5.8123

>AT172836 WP_185114610.1 NZ_CP061714:c304571-304278 [Luteimonas sp. MC1825]
MTKAKEKFSRYDTADYLETEADIAAYLTACAEEDDPALLVAALGDVARARNMTQLAEKTGMTRMGLYKALSGQGNPSFAT
VSKVAHALGLKITVAAA

Download         Length: 294 bp

>AT172836 NZ_CP079991:1144018-1144311 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References