Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 600790..601331 Replicon chromosome
Accession NZ_CP061703
Organism Mesoflavibacter profundi strain YC1039

Toxin (Protein)


Gene name parE Uniprot ID A0A137REF7
Locus tag IFB02_RS02835 Protein ID WP_062623211.1
Coordinates 601029..601331 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A5M7B575
Locus tag IFB02_RS02830 Protein ID WP_028284019.1
Coordinates 600790..601032 (+) Length 81 a.a.

Genomic Context

IFB02_RS02795IFB02_RS02800IFB02_RS02805IFB02_RS02810IFB02_RS02815IFB02_RS02820IFB02_RS02825IFB02_RS02830IFB02_RS02835IFB02_RS02840IFB02_RS02845IFB02_RS02850IFB02_RS02855IFB02_RS02860IFB02_RS02865
Location: 595837..596394 (558 bp)
Type: Others
Protein ID: WP_106687026.1
Location: 596659..597372 (714 bp)
Type: Others
Protein ID: WP_191073026.1
Location: 597586..597876 (291 bp)
Type: Others
Protein ID: WP_106687046.1
Location: 597886..598101 (216 bp)
Type: Others
Protein ID: WP_106687025.1
Location: 598254..599123 (870 bp)
Type: Others
Protein ID: WP_106687024.1
Location: 599274..599810 (537 bp)
Type: Others
Protein ID: WP_106687023.1
Location: 599966..600601 (636 bp)
Type: Others
Protein ID: WP_106687022.1
Location: 600790..601032 (243 bp)
Type: Antitoxin
Protein ID: WP_028284019.1
Location: 601029..601331 (303 bp)
Type: Toxin
Protein ID: WP_062623211.1
Location: 601496..601996 (501 bp)
Type: Others
Protein ID: WP_106687020.1
Location: 602154..602801 (648 bp)
Type: Others
Protein ID: WP_106687019.1
Location: 603399..604178 (780 bp)
Type: Others
Protein ID: WP_106687018.1
Location: 604252..604734 (483 bp)
Type: Others
Protein ID: WP_191073027.1
Location: 604925..605359 (435 bp)
Type: Others
Protein ID: WP_106687016.1
Location: 605450..605926 (477 bp)
Type: Others
Protein ID: WP_106687015.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IFB02_RS02795595837..596394+558WP_106687026.1hypothetical protein-
IFB02_RS02800596659..597372+714WP_191073026.1hypothetical protein-
IFB02_RS02805597586..597876+291WP_106687046.1hypothetical protein-
IFB02_RS02810597886..598101+216WP_106687025.1hypothetical protein-
IFB02_RS02815598254..599123+870WP_106687024.1hypothetical protein-
IFB02_RS02820599274..599810+537WP_106687023.1YcxB family protein-
IFB02_RS02825599966..600601+636WP_106687022.1hypothetical protein-
IFB02_RS02830600790..601032+243WP_028284019.1type II toxin-antitoxin system ParD family antitoxinAntitoxin
IFB02_RS02835601029..601331+303WP_062623211.1type II toxin-antitoxin system RelE/ParE family toxinToxin
IFB02_RS02840601496..601996+501WP_106687020.1hypothetical protein-
IFB02_RS02845602154..602801+648WP_106687019.1hypothetical protein-
IFB02_RS02850603399..604178-780WP_106687018.1patatin-like phospholipase family protein-
IFB02_RS02855604252..604734-483WP_191073027.1hypothetical protein-
IFB02_RS02860604925..605359-435WP_106687016.1Hsp20/alpha crystallin family protein-
IFB02_RS02865605450..605926-477WP_106687015.1Hsp20/alpha crystallin family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--563583..61069847115


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-94)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 12257.25 Da        Isoelectric Point: 10.2010

>T172822 WP_062623211.1 NZ_CP061703:601029-601331 [Mesoflavibacter profundi]
MSKNKYRISQQAIEDLDKIWIYTLNKWSKEQADRYYDLIITEIEFIADNFMTGKSAEQTRKNYRVTKIKSHLIFYRKVEN
DIVEIVRILHQRMDIKKRLK

Download         Length: 303 bp

>T172822 NZ_CP079965:c1856546-1856196 [Macrococcus caseolyticus]
ATGAAACGCGGAGATGTTTTTTTGGCTGATCTGTCACCAGTGAAGGGATCTGAACAAGGCGGTAAACGCCCCGTCGTTAT
TATTCAGAATAATATAGGGAATAAATATAGTCCTACTGTGATTGTAGCGGCAATTACTGCAAAGATTAATAAGGCAAAAA
TCCCCACCCATGTTGAAATTGGCAAGGCAACGCATCGCTTAGAAAAGGATTCGGTAATACTGCTGGAACAAATTAGAACC
ATTGATAAGAATAGGTTGATTGATCATTTAACTGTGCTTGATAAGGCGAAGATGAAAGAAGTGGATACTGCACTTATAAT
TAGTTTAGGTTTATCAATCGATAGTGAATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9306.49 Da        Isoelectric Point: 6.8826

>AT172822 WP_028284019.1 NZ_CP061703:600790-601032 [Mesoflavibacter profundi]
MGKNTSISLGNHFEDFIREEVNSGRYGSVSEVIRSALRLLEREEKKERELIKALEVGENSGFVENFDPKQHLKELHRKHL

Download         Length: 243 bp

>AT172822 NZ_CP079965:c1856687-1856547 [Macrococcus caseolyticus]
ATGAGCCAGAAGCTAGAACAAATGCTGATAGAAGGTTATCAATCAATGGCAGAGATAAATTTATCGATAGCATCAGAACA
TTATGTATTAGAATGCGAAGTTACTGATAACCATCAGACATATACCTTTGATGGTGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A137REF7

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5M7B575

References