Detailed information of TA system TA172787

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 459396..460037
• Replicon: chromosome
• Accession: NZ_CP061681
• Organism: Acinetobacter seifertii strain AS9

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: IC766_RS02250
• Protein ID: WP_077168983.1
• Coordinates: 459648..460037 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: IC766_RS02245
• Protein ID: WP_151276929.1
• Coordinates: 459396..459641 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IC766_RS02225	454897..455904	+	1008	WP_004705386.1	DNA-directed RNA polymerase subunit alpha	-
IC766_RS02230	455923..456300	+	378	WP_002049717.1	50S ribosomal protein L17	-
IC766_RS02235	456482..457972	+	1491	WP_077168981.1	NAD(P)/FAD-dependent oxidoreductase	-
IC766_RS02240	458022..459194	-	1173	WP_077168982.1	acyl-CoA dehydrogenase family protein	-
IC766_RS02245	459396..459641	+	246	WP_151276929.1	succinate dehydrogenase assembly factor 2	Antitoxin
IC766_RS02250	459648..460037	+	390	WP_077168983.1	hypothetical protein	Toxin
IC766_RS02255	460806..461891	+	1086	WP_019457778.1	hypothetical protein	-
IC766_RS02260	461976..462542	+	567	WP_004705397.1	rhombosortase	-
IC766_RS02265	462730..464925	+	2196	WP_019457776.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15626.79 Da
• Isoelectric Point: 9.8344

>T172787 WP_077168983.1 NZ_CP061681:459648-460037 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Nucleotide

• Length: 390 bp

>T172787 NZ_CP079924:c4129986-4129813 [Escherichia sp. TC-EC600-tetX4]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9802.20 Da
• Isoelectric Point: 5.1802

>AT172787 WP_151276929.1 NZ_CP061681:459396-459641 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT172787 NZ_CP079924:c4130310-4130014 [Escherichia sp. TC-EC600-tetX4]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGATT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG