Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 459519..460160 Replicon chromosome
Accession NZ_CP061675
Organism Acinetobacter seifertii strain AS17

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC768_RS02255 Protein ID WP_077168983.1
Coordinates 459771..460160 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC768_RS02250 Protein ID WP_151276929.1
Coordinates 459519..459764 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC768_RS02230 455020..456027 + 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -
IC768_RS02235 456046..456423 + 378 WP_002049717.1 50S ribosomal protein L17 -
IC768_RS02240 456605..458095 + 1491 WP_077168981.1 NAD(P)/FAD-dependent oxidoreductase -
IC768_RS02245 458145..459317 - 1173 WP_077168982.1 acyl-CoA dehydrogenase family protein -
IC768_RS02250 459519..459764 + 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC768_RS02255 459771..460160 + 390 WP_077168983.1 hypothetical protein Toxin
IC768_RS02260 460929..462014 + 1086 WP_019457778.1 hypothetical protein -
IC768_RS02265 462099..462665 + 567 WP_004705397.1 rhombosortase -
IC768_RS02270 462853..465048 + 2196 WP_019457776.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15626.79 Da        Isoelectric Point: 9.8344

>T172782 WP_077168983.1 NZ_CP061675:459771-460160 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T172782 NZ_CP079924:3395377-3395595 [Escherichia sp. TC-EC600-tetX4]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172782 WP_151276929.1 NZ_CP061675:459519-459764 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172782 NZ_CP079924:3394977-3395351 [Escherichia sp. TC-EC600-tetX4]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References