Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 497478..498119 Replicon chromosome
Accession NZ_CP061664
Organism Acinetobacter seifertii strain AS28

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC772_RS02450 Protein ID WP_191016476.1
Coordinates 497730..498119 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC772_RS02445 Protein ID WP_151276929.1
Coordinates 497478..497723 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC772_RS02425 492980..493987 + 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -
IC772_RS02430 494006..494383 + 378 WP_002049717.1 50S ribosomal protein L17 -
IC772_RS02435 494565..496055 + 1491 WP_039253594.1 NAD(P)/FAD-dependent oxidoreductase -
IC772_RS02440 496104..497276 - 1173 WP_191016474.1 acyl-CoA dehydrogenase family protein -
IC772_RS02445 497478..497723 + 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC772_RS02450 497730..498119 + 390 WP_191016476.1 hypothetical protein Toxin
IC772_RS02455 498887..499972 + 1086 WP_019457778.1 hypothetical protein -
IC772_RS02460 500057..500623 + 567 WP_191016477.1 rhombosortase -
IC772_RS02465 500811..503006 + 2196 WP_019457776.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15619.68 Da        Isoelectric Point: 10.1482

>T172778 WP_191016476.1 NZ_CP061664:497730-498119 [Acinetobacter seifertii]
MVNQLNFKLKYSRFSIIFQFFIGLSLAVLFYQLLPILWWLVTVSLLFISFVFFLKRPQLAQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVIYFEGHKTLTSVIWFDQMSLSQWKKLKTLEKFY

Download         Length: 390 bp

>T172778 NZ_CP079924:2286967-2288289 [Escherichia sp. TC-EC600-tetX4]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172778 WP_151276929.1 NZ_CP061664:497478-497723 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172778 NZ_CP079924:2286701-2286967 [Escherichia sp. TC-EC600-tetX4]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References