Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3457253..3457894 Replicon chromosome
Accession NZ_CP061646
Organism Acinetobacter seifertii strain AS39

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC776_RS15975 Protein ID WP_191012192.1
Coordinates 3457253..3457642 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC776_RS15980 Protein ID WP_151276929.1
Coordinates 3457649..3457894 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC776_RS15960 3452366..3454561 - 2196 WP_019457776.1 TRAP transporter large permease subunit -
IC776_RS15965 3454749..3455315 - 567 WP_191012191.1 rhombosortase -
IC776_RS15970 3455400..3456485 - 1086 WP_019457778.1 hypothetical protein -
IC776_RS15975 3457253..3457642 - 390 WP_191012192.1 hypothetical protein Toxin
IC776_RS15980 3457649..3457894 - 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC776_RS15985 3458096..3459268 + 1173 WP_191012193.1 acyl-CoA dehydrogenase family protein -
IC776_RS15990 3459318..3460808 - 1491 WP_191012194.1 NAD(P)/FAD-dependent oxidoreductase -
IC776_RS15995 3460990..3461367 - 378 WP_002049717.1 50S ribosomal protein L17 -
IC776_RS16000 3461386..3462393 - 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15511.51 Da        Isoelectric Point: 9.6261

>T172771 WP_191012192.1 NZ_CP061646:c3457642-3457253 [Acinetobacter seifertii]
MVNQLNFKLKYSRFSIIFQFFIGLGLAALFYQLIPILWWLVAVCLLFISFIFFLKRPQLAQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFVVVYFEGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T172771 NZ_CP079924:c1108315-1107986 [Escherichia sp. TC-EC600-tetX4]
ATGAACACTCTACCTGCTACAATTTCGCAGGCGGCGAAGCCCTGCCTGTCGCCAGTGGCTGTCTGGCAAATGCTACTGAC
ACGCCTGCTGGAACAACACTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATCG
ATGCTGGTATCACTCTGGCCGATGCAGTCAATTTTCTGGTGGAAAAGTACGAACTGGTACGTATCGATCACAGAGGATTT
TCGTGGCAACAACAGTCTCCATATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAA
TGTGAAATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172771 WP_151276929.1 NZ_CP061646:c3457894-3457649 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172771 NZ_CP079924:c1108653-1108336 [Escherichia sp. TC-EC600-tetX4]
ATGAGCAACACCACATGGGGCCTGCAGCGAGATATCACGCCGCGCCTGGGAGCACGTCTGGTGCAGGAGGGCAACCAGCT
GCACTATCTGGCTGACCGGGCCAGTATCACCGGTAAGTTTAGTGACGCCGAATGTCCTAAGCTGGATGTGGTATTTCCAC
ATTTTATCAGCCAGATAGAGTCGATGCTGACCACTGGTGAACTGAATCCCCGCCATGCCCAATGCGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTGCGGCTACGTATACATCGCTGTTTACCCCACTCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References