Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3658796..3659437 Replicon chromosome
Accession NZ_CP061640
Organism Acinetobacter seifertii strain AS40

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC777_RS17525 Protein ID WP_077168983.1
Coordinates 3658796..3659185 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC777_RS17530 Protein ID WP_151276929.1
Coordinates 3659192..3659437 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC777_RS17510 3653908..3656103 - 2196 WP_019457776.1 TRAP transporter large permease subunit -
IC777_RS17515 3656291..3656857 - 567 WP_004705397.1 rhombosortase -
IC777_RS17520 3656942..3658027 - 1086 WP_019457778.1 hypothetical protein -
IC777_RS17525 3658796..3659185 - 390 WP_077168983.1 hypothetical protein Toxin
IC777_RS17530 3659192..3659437 - 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC777_RS17535 3659639..3660811 + 1173 WP_077168982.1 acyl-CoA dehydrogenase family protein -
IC777_RS17540 3660861..3662351 - 1491 WP_077168981.1 NAD(P)/FAD-dependent oxidoreductase -
IC777_RS17545 3662533..3662910 - 378 WP_002049717.1 50S ribosomal protein L17 -
IC777_RS17550 3662929..3663936 - 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15626.79 Da        Isoelectric Point: 9.8344

>T172769 WP_077168983.1 NZ_CP061640:c3659185-3658796 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T172769 NZ_CP079924:844945-845352 [Escherichia sp. TC-EC600-tetX4]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172769 WP_151276929.1 NZ_CP061640:c3659437-3659192 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172769 NZ_CP079924:844698-844964 [Escherichia sp. TC-EC600-tetX4]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References