Detailed information of TA system TA172763

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3653504..3654145
• Replicon: chromosome
• Accession: NZ_CP061629
• Organism: Acinetobacter seifertii strain AS47

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: IC780_RS17505
• Protein ID: WP_077168983.1
• Coordinates: 3653504..3653893 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: IC780_RS17510
• Protein ID: WP_151276929.1
• Coordinates: 3653900..3654145 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IC780_RS17490	3648616..3650811	-	2196	WP_019457776.1	TRAP transporter large permease subunit	-
IC780_RS17495	3650999..3651565	-	567	WP_004705397.1	rhombosortase	-
IC780_RS17500	3651650..3652735	-	1086	WP_019457778.1	hypothetical protein	-
IC780_RS17505	3653504..3653893	-	390	WP_077168983.1	hypothetical protein	Toxin
IC780_RS17510	3653900..3654145	-	246	WP_151276929.1	succinate dehydrogenase assembly factor 2	Antitoxin
IC780_RS17515	3654347..3655519	+	1173	WP_077168982.1	acyl-CoA dehydrogenase family protein	-
IC780_RS17520	3655569..3657059	-	1491	WP_077168981.1	NAD(P)/FAD-dependent oxidoreductase	-
IC780_RS17525	3657241..3657618	-	378	WP_002049717.1	50S ribosomal protein L17	-
IC780_RS17530	3657637..3658644	-	1008	WP_004705386.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15626.79 Da
• Isoelectric Point: 9.8344

>T172763 WP_077168983.1 NZ_CP061629:c3653893-3653504 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Nucleotide

• Length: 390 bp

>T172763 NZ_CP079923:c1558161-1557907 [Streptococcus pneumoniae]
ATGCTACTCAAGTTTACAGAAGATGCCTGGGCAGATTATTGCTACTGGCAAAACCAAGATAAAAAAACACTAAAAAGAAT
CAATAAATTAATCAAGGATATTCAACGCGATCCATTTACAGGAATAGGAAAACCAGAGCCACTCAAATATGATTACCAAG
GAGCCTGGTCACGGCGTATTGATGCAGAAAATCGCTTGATTTATATGATGGATGGAGATAGCGTGGCTTTCTTGTCCTTT
AAAGATCATTACTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9802.20 Da
• Isoelectric Point: 5.1802

>AT172763 WP_151276929.1 NZ_CP061629:c3654145-3653900 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT172763 NZ_CP079923:c1558419-1558165 [Streptococcus pneumoniae]
ATGGAAGCAGTCCTTTACTCAACATTCCGAAATCATTTAAAGGACTACATGAAGAAGGTAAATGATGAATTTGAGCCTTT
GACGGTGGTCAATAAAAATCCAGATGAGGACATTGTAGTTCTTTCAAAGAGCGAATGGGACAGTATTCAGGAAACCCTGA
GAATCGCCCAAAATAAGGAGTTATCAGACAAGGTTTTACGAGGAATGGCTCAAGTCCGTGCTGGAAGCACTCAGGTCCAT
GTGATTGAGGAGTGA