Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3439766..3440407 Replicon chromosome
Accession NZ_CP061626
Organism Acinetobacter seifertii strain AS48

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC781_RS16225 Protein ID WP_191010509.1
Coordinates 3439766..3440155 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC781_RS16230 Protein ID WP_151276929.1
Coordinates 3440162..3440407 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC781_RS16205 3435296..3436504 + 1209 WP_000343018.1 IS256-like element ISAba26 family transposase -
IC781_RS16210 3436529..3437074 - 546 WP_191010506.1 hypothetical protein -
IC781_RS16215 3437262..3437828 - 567 WP_191010507.1 rhombosortase -
IC781_RS16220 3437913..3438998 - 1086 WP_191010508.1 hypothetical protein -
IC781_RS16225 3439766..3440155 - 390 WP_191010509.1 hypothetical protein Toxin
IC781_RS16230 3440162..3440407 - 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC781_RS16235 3440609..3441781 + 1173 WP_191010510.1 acyl-CoA dehydrogenase family protein -
IC781_RS16240 3441830..3443320 - 1491 WP_191010511.1 NAD(P)/FAD-dependent oxidoreductase -
IC781_RS16245 3443502..3443879 - 378 WP_002049717.1 50S ribosomal protein L17 -
IC781_RS16250 3443898..3444905 - 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3435296..3436504 1208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15663.75 Da        Isoelectric Point: 9.8449

>T172759 WP_191010509.1 NZ_CP061626:c3440155-3439766 [Acinetobacter seifertii]
MINQLNFKLKYSRFSIIFQFFIGLSLAALFYQLIPILWWLVTVCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVIYFEGHKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T172759 NZ_CP079922:c1568075-1567821 [Streptococcus pneumoniae]
ATGCTACTCAAGTTTACAGAAGATGCCTGGGCAGATTATTGCTACTGGCAAAACCAAGATAAAAAAACACTAAAAAGAAT
CAATAAATTAATCAAGGATATTCAACGCGATCCATTTACAGGAATAGGAAAACCAGAGCCACTCAAATATGATTACCAAG
GAGCCTGGTCACGGCGTATTGATGCAGAAAATCGCTTGATTTATATGATGGATGGAGATAGCGTGGCTTTCTTGTCCTTT
AAAGATCATTACTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172759 WP_151276929.1 NZ_CP061626:c3440407-3440162 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172759 NZ_CP079922:c1568333-1568079 [Streptococcus pneumoniae]
ATGGAAGCAGTCCTTTACTCAACATTCCGAAATCATTTAAAGGACTACATGAAGAAGGTAAATGATGAATTTGAGCCTTT
GACGGTGGTCAATAAAAATCCAGATGAGGACATTGTAGTTCTTTCAAAGAGCGAATGGGACAGTATTCAGGAAACCCTGA
GAATCGCCCAAAATAAGGAGTTATCAGACAAGGTTTTACGAGGAATGGCTCAAGTCCGTGCTGGAAGCACTCAGGTCCAT
GTGATTGAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References