Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3689293..3689934 Replicon chromosome
Accession NZ_CP061620
Organism Acinetobacter seifertii strain AS49

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC782_RS17765 Protein ID WP_077168983.1
Coordinates 3689293..3689682 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC782_RS17770 Protein ID WP_151276929.1
Coordinates 3689689..3689934 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC782_RS17750 3684405..3686600 - 2196 WP_019457776.1 TRAP transporter large permease subunit -
IC782_RS17755 3686788..3687354 - 567 WP_004705397.1 rhombosortase -
IC782_RS17760 3687439..3688524 - 1086 WP_019457778.1 hypothetical protein -
IC782_RS17765 3689293..3689682 - 390 WP_077168983.1 hypothetical protein Toxin
IC782_RS17770 3689689..3689934 - 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC782_RS17775 3690136..3691308 + 1173 WP_077168982.1 acyl-CoA dehydrogenase family protein -
IC782_RS17780 3691358..3692848 - 1491 WP_077168981.1 NAD(P)/FAD-dependent oxidoreductase -
IC782_RS17785 3693030..3693407 - 378 WP_002049717.1 50S ribosomal protein L17 -
IC782_RS17790 3693426..3694433 - 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15626.79 Da        Isoelectric Point: 9.8344

>T172756 WP_077168983.1 NZ_CP061620:c3689682-3689293 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T172756 NZ_CP079921:1883264-1883731 [Actinobacillus pleuropneumoniae]
ATGCACGCACCGGAACTGCTTTCCGAGCAACATATTGTGCGATATTTTCAATGTGGTGAGGTCGTGCTAGACCAATGGCT
ACAACGTACTGCATTGAAAAATCAGCAAAATAATGCCAGTAAAACCTTTGTTGTGTGTGATGAAAATAAACAGGTGATGG
GATTTTATTGTTTATCTGCCGGTTCGGTGAGCCATCAGTTTGTTGCAGGTGCCTTAAGACGTAATATGCCCGATCCGATT
CCCGTGATTATTTTAGGTAGATTAGCGGTCGATTGTTCGGCACAGGGTAAGCAGTTAGGCGTATCAATGTTAAAAGATGC
GGTCTTAAAATCGAAGACGGTGGCGAACCAAATCGGGGTAAAAGCATTGCTTGTTCATGCGTTAAACCCGCAAGCAAAAC
AATTTTATTTAAAGTATGGTTTTTCATGTTCACCCATTGATGAGATGGTATTAATGTTAAAACTCTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172756 WP_151276929.1 NZ_CP061620:c3689934-3689689 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172756 NZ_CP079921:1883000-1883260 [Actinobacillus pleuropneumoniae]
ATGAGAACTGCGCCAATTAATTTACGAGCGATGCCTGATCAGCGTGATTTAATTGATTATGCGGCAAGCATTTTAGGTAA
AACACGTTCTGACTTTATGTTAGAAACCGCCTGCCAAGCTGCCCAAAATGTGATTTTAGATCGTACCGTTTTCCAATTAA
ATGAGCAGGCTTTCGAGCAATTTAACCGATTGCTAGAACAGCCAACAGCAGATAATCCGGGGTTAGATAAACTGTTAAAT
ACCAAAGCGGTGTGGGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References