Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-paaA/RelE(toxin)
Location 35715..36165 Replicon plasmid pAS51-3
Accession NZ_CP061616
Organism Acinetobacter seifertii strain AS51

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IC783_RS21945 Protein ID WP_059273176.1
Coordinates 35715..35990 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag IC783_RS21950 Protein ID WP_004949557.1
Coordinates 35977..36165 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC783_RS21935 32103..35078 + 2976 WP_064851181.1 conjugal transfer protein TraG N-terminal domain-containing protein -
IC783_RS21940 35123..35671 + 549 WP_004949551.1 transglycosylase SLT domain-containing protein -
IC783_RS21945 35715..35990 - 276 WP_059273176.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IC783_RS21950 35977..36165 - 189 WP_004949557.1 hypothetical protein Antitoxin
IC783_RS21955 36285..36983 - 699 WP_004949560.1 DNA adenine methylase -
IC783_RS21960 37431..37964 - 534 WP_004949563.1 hypothetical protein -
IC783_RS21965 38395..38718 + 324 WP_004949566.1 H-NS histone family protein -
IC783_RS21970 38827..39105 - 279 WP_004949569.1 hypothetical protein -
IC783_RS21975 39151..39426 - 276 WP_004949572.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..66816 66816


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-79)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10438.94 Da        Isoelectric Point: 5.0825

>T172755 WP_059273176.1 NZ_CP061616:c35990-35715 [Acinetobacter seifertii]
MLIVEWTPNAIEDLEAISDYIAEHNPIAAYNLEDHILKCAESLSEHPYKGVSGRVVGTREMLVHPNYWLIYEVSDMIKIK
GVLHTRKSYPD

Download         Length: 276 bp

>T172755 NZ_CP079921:c1780802-1780404 [Actinobacillus pleuropneumoniae]
ATGCTGGCTTATATGCTTGATACTAATATTGCGATTTATGTGATTAAACGCAGACCTATTGAAGTGCTGGATAAGTTTAA
TTTAAATTCTACTCGTCTTTGTGTAAGTAGTATCACTGCAGCGGAGTTGTATTATGGTGCAGAGAAAAGCCAGTTTCCGG
AACGAAATATGGCAGTAATTGAGGATTTTCTTTCTCGTTTAACGATTCTTGATTATACGCATAAGGCGGCTACTCACTTT
GGCAATATTAAAGCACATTTATCTAAGCAAGGTAAGATCATTGGCGAGAACGATATTCATATTGCCGCACATGCAAGAAG
TGAAGGACTCGTATTAGTGACCAATAACTTGCGTGCATTTGAACGTGTGGAAGGATTGCGATTAGATAATTGGGTATAG

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7309.13 Da        Isoelectric Point: 7.2031

>AT172755 WP_004949557.1 NZ_CP061616:c36165-35977 [Acinetobacter seifertii]
MNTVFDPIVSEFDSSDHESEYNAWFKAKIEKSMADTRPTVPHDQVVARLKKRREERTTNVNR

Download         Length: 189 bp

>AT172755 NZ_CP079921:c1781032-1780802 [Actinobacillus pleuropneumoniae]
ATGGAAGCATCGGTATTTATGACAAACCGTAGTCAGGCGGTACGATTACCTGCAGAAGTGCGTTTTGCAAGTGATGTAAA
AAAACTTTCTGTAAGAGTGGTAGGCAATGAACGTATTTTGGCTCCAATTAACCAAAGTTGGGATAGCTTCTTTCTGAGTT
CGGCAACGGTAAGCGATGATTTCATGACAGAGCGTGAAATCAGCATTCAGCCCGAACGTGAGGGACTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References