Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 482521..483162 Replicon chromosome
Accession NZ_CP061603
Organism Acinetobacter seifertii strain AS53

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag IC785_RS02340 Protein ID WP_077168983.1
Coordinates 482773..483162 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag IC785_RS02335 Protein ID WP_151276929.1
Coordinates 482521..482766 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC785_RS02315 478022..479029 + 1008 WP_004705386.1 DNA-directed RNA polymerase subunit alpha -
IC785_RS02320 479048..479425 + 378 WP_002049717.1 50S ribosomal protein L17 -
IC785_RS02325 479607..481097 + 1491 WP_077168981.1 NAD(P)/FAD-dependent oxidoreductase -
IC785_RS02330 481147..482319 - 1173 WP_077168982.1 acyl-CoA dehydrogenase family protein -
IC785_RS02335 482521..482766 + 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
IC785_RS02340 482773..483162 + 390 WP_077168983.1 hypothetical protein Toxin
IC785_RS02345 483931..485016 + 1086 WP_019457778.1 hypothetical protein -
IC785_RS02350 485101..485667 + 567 WP_004705397.1 rhombosortase -
IC785_RS02355 485855..488050 + 2196 WP_019457776.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15626.79 Da        Isoelectric Point: 9.8344

>T172751 WP_077168983.1 NZ_CP061603:482773-483162 [Acinetobacter seifertii]
MINQLNFKLKYSRFAIVFQFFIGLCLAALFYQLIPILWWLVTLCLLFISFIFFLKRPQLVQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFKGDKTLTSVIWFDQMSLSQWKQLKTLEKFY

Download         Length: 390 bp

>T172751 NZ_CP079921:1441746-1441997 [Actinobacillus pleuropneumoniae]
ATGCAAGCAATAACCTACACAGAAGCACGCCAAAATCTAGCCGGTACGATGTCAAAAGTAGCAGAAGATTTTGAGCCTAT
TTTAATTACAAGAAGCAAGGGCGGAAATTGCGTACTTATGTCGTATGAGCAGTATTGTTCACTTGAAGAAACCGCCTATT
TGATGCGTTCACCCACCAATGCAAAACGGCTATTGGATAGTGTGGCGGAATTAAGACAGGGACAAGGCATTGAAAGAGAG
CTAATCGAATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT172751 WP_151276929.1 NZ_CP061603:482521-482766 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT172751 NZ_CP079921:1441994-1442254 [Actinobacillus pleuropneumoniae]
ATGAAGCTAACTTTCTCGTCTAATGCGTGGGAAGATTATTTATACTGGCAAAAAACCGATAAAATAATTTTGAAACGTAT
AAACAGCCTGATCAAAGATATTCAACGCCAACCATTCGAAGGCATAGGAAAACTGGAGCCGCTAAAATTCAATCTTTCGG
GATTTTGGTCAAGGCGAATCAATGAAGAACACCGCTTAATTTACAGCGTGGAAGATGAAGCAATTTTAATAGTAGCGTGT
AGATACCATTATGATCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References