Detailed information of TA system TA172749

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 458260..458901
• Replicon: chromosome
• Accession: NZ_CP061596
• Organism: Acinetobacter seifertii strain AS59

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: IC788_RS02240
• Protein ID: WP_151749378.1
• Coordinates: 458512..458901 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: IC788_RS02235
• Protein ID: WP_151276929.1
• Coordinates: 458260..458505 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IC788_RS02215	453759..454766	+	1008	WP_004705386.1	DNA-directed RNA polymerase subunit alpha	-
IC788_RS02220	454785..455162	+	378	WP_002049717.1	50S ribosomal protein L17	-
IC788_RS02225	455344..456834	+	1491	WP_019457782.1	NAD(P)/FAD-dependent oxidoreductase	-
IC788_RS02230	456883..458055	-	1173	WP_191001074.1	acyl-CoA dehydrogenase family protein	-
IC788_RS02235	458260..458505	+	246	WP_151276929.1	succinate dehydrogenase assembly factor 2	Antitoxin
IC788_RS02240	458512..458901	+	390	WP_151749378.1	hypothetical protein	Toxin
IC788_RS02245	459670..460755	+	1086	WP_191001075.1	hypothetical protein	-
IC788_RS02250	460840..461406	+	567	WP_004705397.1	rhombosortase	-
IC788_RS02255	461594..463789	+	2196	WP_191001076.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15619.63 Da
• Isoelectric Point: 10.0179

>T172749 WP_151749378.1 NZ_CP061596:458512-458901 [Acinetobacter seifertii]
MVNQLNFKLKYSRFSIIFQFFIGLSLAVLFYQLLPILWWLVTVSLLFISFVFFLKRPQLAQIAYLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVIYFEGHKTLTSVIWFDQMSLSQWKQLKTLEKFY

Nucleotide

• Length: 390 bp

>T172749 NZ_CP079903:3388463-3388645 [Pseudomonas juntendi]
GTGCAAAGCAGGCAGTTGATCAAGGAGCTTGAAGCAGCTGGATGGGTTCTGAAACGTGTCACTGGAAGCCACCACATCTT
CAAACACCCCAACAACCCAAACTCGATACCAGTGCCACACCCCAAGAAGGATCTACCGATCGGCACGGTAAAGAGCATCA
AGGAACGAGCCGGGTTGAAATAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9802.20 Da
• Isoelectric Point: 5.1802

>AT172749 WP_151276929.1 NZ_CP061596:458260-458505 [Acinetobacter seifertii]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT172749 NZ_CP079903:3388683-3389084 [Pseudomonas juntendi]
ATGCAATACCCAATCTGCATCGAGTGGGGCGACGAAAACACCGCCACCGGCATTCAGATCCCCGATATTCCAGGCGCTGT
TACCGCGGGCGACACCTTCGAGGAGGCCTATACCTCTGCCGTCGAGGTCGCCCATATCATGCTGGAAGAGATCGCCAGTA
ACGGCCAGGCCATCCCGATGCCAACCAGCGCCGCGGCCCACCGGGACAATCCCGACTTCGCTGACATGGGCTGGGGCATG
CTGGAGATCGACATCACGCCATACCTGGGCAAGACCGAAAAGGTCAATGTCACCCTGCCGGGCTTCGTCATCCAGAAGAT
CGACCAGTACGTGCGCGATCACAACGTGAAAAGCCGGTCGTCGTTCCTGGCAGATGCTGCCATGGAAAAGCTGGGCCGTT
AA